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(2S, 4S)-4-Hydroxytetrahydrofuran-2-methanol, an organic compound with the molecular formula C5H12O3, belongs to the class of tetrahydrofurans, which are cyclic ethers. This specific compound features a hydroxyl group and a methyl group attached to the tetrahydrofuran ring. Its (2S, 4S) stereochemistry endows it with unique properties, making it a valuable building block and intermediate in the synthesis of various pharmaceuticals and fine chemicals. It plays a significant role in the field of organic chemistry and has a range of industrial applications.

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  • 204509-08-0 Structure
  • Basic information

    1. Product Name: (2S, 4S)-4-HYDROXYTETRAHYDROFURAN-2-METHANOL
    2. Synonyms: (2S, 4S)-4-HYDROXYTETRAHYDROFURAN-2-METHANOL;(3S,5S)-5-(hydroxyMethyl)tetrahydrofuran-3-ol;1,4-Anhydro-3-deoxy-D-threo-pentitol
    3. CAS NO:204509-08-0
    4. Molecular Formula: C5H10O3
    5. Molecular Weight: 118.13
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 204509-08-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 275.1±15.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.239±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: 14.33±0.40(Predicted)
    10. CAS DataBase Reference: (2S, 4S)-4-HYDROXYTETRAHYDROFURAN-2-METHANOL(CAS DataBase Reference)
    11. NIST Chemistry Reference: (2S, 4S)-4-HYDROXYTETRAHYDROFURAN-2-METHANOL(204509-08-0)
    12. EPA Substance Registry System: (2S, 4S)-4-HYDROXYTETRAHYDROFURAN-2-METHANOL(204509-08-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 204509-08-0(Hazardous Substances Data)

204509-08-0 Usage

Uses

Used in Pharmaceutical Industry:
(2S, 4S)-4-Hydroxytetrahydrofuran-2-methanol is used as a building block and intermediate for the synthesis of various pharmaceuticals. Its unique stereochemistry and functional groups make it suitable for the development of new drugs with specific therapeutic properties.
Used in Fine Chemicals Industry:
In the fine chemicals industry, (2S, 4S)-4-Hydroxytetrahydrofuran-2-methanol serves as a key intermediate in the production of specialty chemicals. Its versatility in chemical reactions allows for the creation of a wide range of high-value products.
Used in Organic Chemistry Research:
(2S, 4S)-4-Hydroxytetrahydrofuran-2-methanol is utilized as a research compound in organic chemistry. Its distinct properties and reactivity make it an important tool for studying various chemical reactions and mechanisms, contributing to the advancement of scientific knowledge in the field.

Check Digit Verification of cas no

The CAS Registry Mumber 204509-08-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,4,5,0 and 9 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 204509-08:
(8*2)+(7*0)+(6*4)+(5*5)+(4*0)+(3*9)+(2*0)+(1*8)=100
100 % 10 = 0
So 204509-08-0 is a valid CAS Registry Number.

204509-08-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name (3S,5S)-5-(hydroxymethyl)oxolan-3-ol

1.2 Other means of identification

Product number -
Other names (3S,5S)-5-(hydroxymethyl)tetrahydrofuran-3-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:204509-08-0 SDS

204509-08-0Downstream Products

204509-08-0Relevant articles and documents

Intramolecular addition of carbon radicals to aldehydes: synthesis of enantiopure tetrahydrofuran-3-ols

Tiecco, Marcello,Testaferri, Lorenzo,Marini, Francesca,Sternativo, Silvia,Santi, Claudio,Bagnoli, Luana,Temperini, Andrea

, p. 5482 - 5489 (2008/01/07)

A simple and efficient substrate-controlled asymmetric synthesis of enantiopure tetrahydrofuran-3-ols by a 5-exo-trig radical cyclization is described. This cyclization occurs when a δ-carbon radical adds intramolecularly to the carbonyl group of an aldeh

Enantiospecific total synthesis of L-2',3'-dideoxyisonucleosides via regioselective opening of optically active C2-symmetric 1,4-pentadiene bis- epoxide

Jung,Kretschik

, p. 2975 - 2981 (2007/10/03)

A new method for the synthesis of L-2',3'-dideoxyisonucleosides is described. The readily available, optically active C2-symmetric bis-epoxide (2S,4S)-1,2:4,5-diepoxypentane (5) was prepared by a short route from readily available starting mate

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