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Propargyl-PEG8-acid is a versatile chemical compound featuring an alkyne group and an acid group, with the acid group capable of derivatizing amine-containing molecules through activation by EDC or HATU. The alkyne group allows for reactions with azides via copper-catalyzed Click Chemistry, while the PEG units enhance the molecule's solubility in aqueous environments.

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  • 2055014-94-1 Structure
  • Basic information

    1. Product Name: Propargyl-PEG8-acid
    2. Synonyms: Propargyl-PEG8-acid;Propargyl-PEG7-CH2CH2COOH
    3. CAS NO:2055014-94-1
    4. Molecular Formula: C20H36O10
    5. Molecular Weight: 436.49384
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 2055014-94-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: Soluble in Water, DMSO, DCM, DMF
    9. CAS DataBase Reference: Propargyl-PEG8-acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: Propargyl-PEG8-acid(2055014-94-1)
    11. EPA Substance Registry System: Propargyl-PEG8-acid(2055014-94-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 2055014-94-1(Hazardous Substances Data)

2055014-94-1 Usage

Uses

Used in Bioconjugation:
Propargyl-PEG8-acid is used as a bioconjugation agent for attaching amine-containing biomolecules to other molecules or surfaces. The acid group facilitates the formation of stable amide bonds with amine groups, enabling the creation of various bioconjugates for research and therapeutic applications.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Propargyl-PEG8-acid is used as a component in drug delivery systems to improve the solubility and bioavailability of hydrophobic drugs. The PEG units enhance the stability and circulation time of drug carriers, while the alkyne group allows for the incorporation of targeting ligands or imaging agents through Click Chemistry.
Used in Materials Science:
In materials science, Propargyl-PEG8-acid is used as a building block for the synthesis of functional polymers and materials. The alkyne group can be employed in Click Chemistry to create well-defined polymer architectures, while the PEG units provide improved solubility and biocompatibility.
Used in Chemical Biology:
In chemical biology, Propargyl-PEG8-acid is used as a modular component for the construction of chemical probes and tools. The alkyne group enables the attachment of various functional groups through Click Chemistry, allowing for the development of novel probes for studying biological systems.

Check Digit Verification of cas no

The CAS Registry Mumber 2055014-94-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,0,5,5,0,1 and 4 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2055014-94:
(9*2)+(8*0)+(7*5)+(6*5)+(5*0)+(4*1)+(3*4)+(2*9)+(1*4)=121
121 % 10 = 1
So 2055014-94-1 is a valid CAS Registry Number.

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