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CAS

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2246335-51-1

(S)-2-<4,5-dihydro-4-(1,1-dimethylethyl)oxazol-2-yl>quinoline, also known as (-)-OSU6162, is a novel chemical compound with potential pharmacological applications. It is characterized by its unique molecular structure that includes a quinoline ring fused with an oxazol ring, which contributes to its potential biological activities.

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  • 2246335-51-1 Structure

  • Basic information

    1. Product Name: (S)-2-<4,5-dihydro-4-(1,1-dimethylethyl)oxazol-2-yl>quinoline
    2. Synonyms:
    3. CAS NO:2246335-51-1
    4. Molecular Formula:
    5. Molecular Weight: 254.332
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 2246335-51-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (S)-2-<4,5-dihydro-4-(1,1-dimethylethyl)oxazol-2-yl>quinoline(CAS DataBase Reference)
    10. NIST Chemistry Reference: (S)-2-<4,5-dihydro-4-(1,1-dimethylethyl)oxazol-2-yl>quinoline(2246335-51-1)
    11. EPA Substance Registry System: (S)-2-<4,5-dihydro-4-(1,1-dimethylethyl)oxazol-2-yl>quinoline(2246335-51-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 2246335-51-1(Hazardous Substances Data)

2246335-51-1 Usage

Uses

Used in Pharmaceutical Industry:
(S)-2-<4,5-dihydro-4-(1,1-dimethylethyl)oxazol-2-yl>quinoline is used as a dopamine stabilizer for the treatment of neurological and psychiatric disorders. Its application is based on its potential to modulate dopamine levels, which are often disrupted in conditions like Parkinson's disease and schizophrenia.
Used in Cognitive Function Enhancement:
In the field of cognitive science, (S)-2-<4,5-dihydro-4-(1,1-dimethylethyl)oxazol-2-yl>quinoline is used to improve cognitive function. (S)-2-<4,5-dihydro-4-(1,1-dimethylethyl)oxazol-2-yl>quinoline has shown promise in enhancing cognitive abilities, which could be beneficial for individuals suffering from cognitive decline or other related conditions.
Used in Addiction Treatment:
Within the addiction treatment sector, (S)-2-<4,5-dihydro-4-(1,1-dimethylethyl)oxazol-2-yl>quinoline is being investigated for its potential use in treating drug addiction. (S)-2-<4,5-dihydro-4-(1,1-dimethylethyl)oxazol-2-yl>quinoline's ability to interact with the dopamine system, which is often implicated in addiction, makes it a candidate for further research and development in this area.

Check Digit Verification of cas no

The CAS Registry Mumber 2246335-51-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,2,4,6,3,3 and 5 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 2246335-51:
(9*2)+(8*2)+(7*4)+(6*6)+(5*3)+(4*3)+(3*5)+(2*5)+(1*1)=151
151 % 10 = 1
So 2246335-51-1 is a valid CAS Registry Number.

2246335-51-1Downstream Products

2246335-51-1Relevant articles and documents

Pd-catalyzed asymmetric aza-Wacker-type cyclization reaction of olefinic tosylamides

Jiang, Feng,Wu, Zhengxing,Zhang, Wanbin

scheme or table, p. 5124 - 5126 (2010/11/16)

The Pd-catalyzed asymmetric aza-Wacker-type cyclization reaction of the olefinic tosylamides with molecular oxygen as the green oxidant was developed. Under the optimized conditions, excellent catalytic activity and good enantioselectivity with up to 74%

Pd(II)/tBu-quinolineoxazoline: An Air-Stable and modular chiral catalyst system for enantioselective oxidative cascade cyclization

He, Wei,Yip, Kai-Tai,Zhu, Nian-Yong,Yang, Dan

supporting information; experimental part, p. 5626 - 5628 (2010/03/02)

[Chemical Equation Presented] An air-stable and structurally tunable chiral tBu-quinolineoxazoline/Pd(II) catalyst system has been developed for the enantioselective oxidative cascade cyclization of a variety of disubstituted olefinic substrates, with the apparent advantages of good yields and excellent enantioselectivities (up to 98% ee) and diastereoselectivities (dr >24:1). A transition-state model has also been proposed to account for the excellent stereocontrol.

Palladium(II)-catalyzed enantioselective aerobic dialkoxylation of 2-propenyl phenols: A pronounced effect of copper additives on enantioselectivity

Zhang, Yang,Sigman, Matthew S.

, p. 3076 - 3077 (2008/04/18)

A direct O2-coupled Pd(II)-catalyzed enantioselective dialkoxylation of 2-propenylphenols has been developed by utilizing chiral quinoline oxazoline ligands. A detrimental effect of added copper salts on enantioselectivity was observed which is attributed to the displacement of the chiral ligand off of Pd(II). Copyright

Steric effects of the ligand in the enantioselective palladium-catalyzed allylic alkylation using chiral oxazolinylpyridines

Chelucci, Giorgio,Medici, Serenella,Saba, Antonio

, p. 543 - 550 (2007/10/03)

Eight new chiral oxazolinylpyridines were prepared and assessed in the enantioselective palladium-catalyzed allylic substitution of 1,3- diphenylprop-2-enyl acetate with dimethyl malonate. Catalytic activity and enantioselectivity were found to be highly

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