474709-06-3

• 

• Basic information

  1. Product Name: 6-Bromo-8-fluoroimidazo[1,2-a]pyridine
  2. Synonyms: 6-Bromo-8-fluoroimidazo[1,2-a]pyridine;IMidazo[1,2-a]pyridine, 6-broMo-8-fluoro-
  3. CAS NO:474709-06-3
  4. Molecular Formula: C7H4BrFN2
  5. Molecular Weight: 215.025
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 474709-06-3.mol

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: /
  5. Density: 1.806g/cm³
  6. Refractive Index: 1.664
  7. Storage Temp.: 2-8°C
  8. Solubility: N/A
  9. CAS DataBase Reference: 6-Bromo-8-fluoroimidazo[1,2-a]pyridine(CAS DataBase Reference)
  10. NIST Chemistry Reference: 6-Bromo-8-fluoroimidazo[1,2-a]pyridine(474709-06-3)
  11. EPA Substance Registry System: 6-Bromo-8-fluoroimidazo[1,2-a]pyridine(474709-06-3)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 474709-06-3(Hazardous Substances Data)

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474709-06-3 Usage

Uses

Used in Pharmaceutical Industry:
6-Bromo-8-fluoroimidazo[1,2-a]pyridine is used as a key intermediate in the synthesis of imidazopyrazines. These imidazopyrazines act as adenosine A2A receptor modulators, which have potential therapeutic applications in the treatment of various diseases. By modulating the adenosine A2A receptor, these compounds can potentially influence physiological processes and provide therapeutic benefits for a range of conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 474709-06-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,4,7,0 and 9 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 474709-06:
(8*4)+(7*7)+(6*4)+(5*7)+(4*0)+(3*9)+(2*0)+(1*6)=173
173 % 10 = 3
So 474709-06-3 is a valid CAS Registry Number.

InChI:InChI=1/C7H4BrFN2/c8-5-3-6(9)7-10-1-2-11(7)4-5/h1-4H

474709-06-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	6-Bromo-8-fluoroimidazo[1,2-a]pyridine

1.2 Other means of identification

Product number	-
Other names	QC-7988

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:474709-06-3 SDS

474709-06-3Upstream product

• 474709-05-2 6-bromo-8-fluoro-2,3-dihydroimidazo[1,2-a]pyridine 

474709-06-3Downstream Products

474709-06-3Relevant articles and documents

NITROGENOUS FUSED?RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF

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Page 134, (2008/06/13)

The present invention provides a compound having an excellent inhibitory action on activation of STAT6 and a pharmaceutical composition thereof. Inparticular, it provides a compound represented by the following formula (I), a salt thereof or a hydrate of them. In the formula, X represents a nitrogen-containing condensed aromatic heterocyclic group such as imidazo[1,2-a]pyridine, benzimidazole, quinazoline, quinoline, or 2,1-benzisoxazole and has (R4)n as substituent groups; Y represents a C3-8 cycloalkyl group, C4-8 cycloalkenyl group, 5- to 14-membered non-aromatic heterocyclic group, C6-14 aromatic hydrocarbon cyclic group or 5- to 14-membered aromatic heterocyclic group; n in (R4)n is 0, 1, 2 or 3, and Z groups independently represent (1) hydrogen atom, (2) amino group, (3) halogen atom, (4) hydroxyl group, (5) nitro group, (6) cyano group, (7) azido group, (8) formyl group, (9) hydroxyamino group, (10) sulfamoyl group, (11) guanodino group, (12) oxo group, (13) C2-6 alkenyl group, (14) C1-6 alkoxy group, (15) C1-6 alkylhydroxyamino group, (16) halogenated C1-6 alkyl group, (17) halogenated C2-6 alkenyl group, (18) (i) C3-7cycloalkyl group, (ii) C3-7cycloalkenyl group, (iii) 5- to 14-membered non-aromatic heterocyclic group, each of which may have one or more substituent groups Q, or (19) formula -M1-M2-M3, R1 represents (1) hydrogen atom, (2) halogen atom, (3) hydroxyl group, (4) nitro group, (5) cyano group, (6) halogenated C1-6 alkyl group, (7) C2-6 alkyl group substituted with a hydroxyl or cyano group, (8) C2-6 alkenyl group, or (9) formula -L1-L2-L3, and R2 represents a hydrogen atom or a protecting group; and R3 represents a hydrogen atom, halogen atom, cyano group, amino group, C1-4 alkyl group or halogenated C1-4 alkyl group.

NOVEL COMPOUNDS AS PHARMACEUTICAL AGENTS

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Page 43, (2010/02/07)

The current invention relates to compounds of the formula:(Ia) and the pharmaceutically acceptable salts thereof and their use as TGF-beta signal transduction inhibitors for treating cancer and other diseases in a patient in need thereof by administration of said compounds.

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