918961-25-8Relevant articles and documents
C-H Amination of Nitro Azaheterocyclic Compounds by Vicarious Nucleophilic Substitution
Zhou, Ru-Shuang,Cai, Chun
supporting information, p. 88 - 92 (2021/12/03)
Various nitro azaheterocyclic compounds were subjected to C H amination by vicarious nucleophilic substitution with 4H-1,2,4-triazol-4-amine (ATA). The aminated products were characterized by NMR, mass spectroscopy, and single-crystal X-ray diffraction an
Synthesis and biological evaluation of 5-arylamino-6-chloro-1H-indazole-4,7-diones as inhibitors of protein kinase B/Akt
Ko, Jong Hee,Yeon, Seung Woo,Ryu, Jung Su,Kim, Tae-Yong,Song, Eun-Ha,You, Hea-Jung,Park, Rae-Eun,Ryu, Chung-Kyu
, p. 6001 - 6005 (2007/10/03)
A series of 5-arylamino-6-chloro-1H-indazole-4,7-diones were synthesized and evaluated for their inhibitory activity on protein kinase B/Akt. The compounds exhibited a potent Akt1 inhibitory activity. Further mechanistic study revealed that they might hav