942593-10-4Relevant articles and documents
METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS
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Page/Page column 24-25, (2008/12/07)
A method for repelling arthropods involving treating an object or area with an arthropod repelling effective amount of at least one compound having the formula wherein X is O, S, NH, N-NH2, N-CH3 or CH2, R' is H or alkyl, R" is alkyl, n is 0, 1, 2, 3 or 4, and mixtures thereof, optionally including a earner material or earner. The compound is preferably selected from homopiperazine, 1-methylhomopiperazine, 1-methylpyrrolidine, (R)- (-)-2-methylpiperazine, (S)-(+)-2-methylpiperazine, 2-methylpiperazine, 1 -methylpiperazine, pyrrolidine, 1-methylpiperidine, piperidine, 1-ethylpiperazine, 1-methylimidazolidine, 1- methylthiomorpholine, 1,4-dimethylpiperazine, homopiperidine, imidazolidine, 4- methylpiperidine, thiomoφholine, l-amino-4-methylpiperazine, 4-methylmoipholine, azocane, 2,6-dimethylpiperazine, 2,5-dimethylpiperazine, piperazine, 1-methylhomopiperidine, or mixtures thereof.
Preparation of diamines by lithiation-substitution of imidazolidines and pyrimidines
Ashweek, Neil J.,Coldham, Iain,Haxell, Thomas F.N.,Howard, Steven
, p. 1532 - 1544 (2007/10/03)
The synthesis of chiral 1,2-diamines and 1,3-diamines was achieved from the unsubstituted diamines by way of N-tert-butoxycarbonyl (Boc) substituted imidazolidines (tetrahydroimidazoles) and pyrimidines (hexahydro-1,3-diazines), which were treated with sec-butyllithium to effect deprotonation a- to the N-Boc group, followed by addition of an electrophile to give substituted products that could be hydrolysed under acidic conditions to give the substituted 1,2- or 1,3-diamines. Use of the chiral ligand (-)-sparteine promoted asymmetric deprotonation of the imidazolidine substrates to give, after hydrolysis, enantiomerically enriched 1,2-diamines.
