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3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo-, also known as Bromo-PEG5-alcohol, is a PEG (polyethylene glycol) linker containing a bromide group and a terminal hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media, while the bromide (Br) acts as a good leaving group for nucleophilic substitution reactions. The hydroxyl group allows for further derivatization or replacement with other reactive functional groups.

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  • 957205-14-0 Structure
  • Basic information

    1. Product Name: 3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo-
    2. Synonyms: 3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo-;14-bromo-3,6,9,12-tetraoxatetradecan-1-ol;Bromo-PEG5-alcohol;Br-PEG5-OH
    3. CAS NO:957205-14-0
    4. Molecular Formula: C10H21BrO5
    5. Molecular Weight: 301
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 957205-14-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: Soluble in DCM
    9. CAS DataBase Reference: 3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo-(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo-(957205-14-0)
    11. EPA Substance Registry System: 3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo-(957205-14-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 957205-14-0(Hazardous Substances Data)

957205-14-0 Usage

Uses

Used in Pharmaceutical Industry:
3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromois used as a building block for the synthesis of various pharmaceutical compounds. The hydrophilic PEG spacer enhances the solubility and bioavailability of the resulting compounds, while the bromide group facilitates the attachment of various functional groups through nucleophilic substitution reactions.
Used in Drug Delivery Systems:
3,6,9,12-Tetraoxatecan-1-ol, 14-bromois used as a component in the development of drug delivery systems. The PEG spacer improves the stability and solubility of drug carriers, while the bromide group allows for the attachment of therapeutic agents or targeting moieties through nucleophilic substitution reactions. This enables the design of targeted drug delivery systems with enhanced efficacy and reduced side effects.
Used in Bioconjugation:
3,6,9,12-Tetraoxatecan-1-ol, 14-bromois used as a bioconjugation agent for the attachment of biologically active molecules, such as peptides, proteins, or nucleic acids, to various surfaces or carriers. The hydroxyl group allows for the covalent attachment of these molecules, while the PEG spacer provides steric stabilization and reduces non-specific interactions.
Used in Chemical Synthesis:
3,6,9,12-Tetraoxatecan-1-ol, 14-bromois used as an intermediate in the synthesis of various organic compounds. The bromide group can be replaced with other functional groups through nucleophilic substitution reactions, enabling the preparation of a wide range of PEGylated compounds with diverse applications in materials science, pharmaceuticals, and other fields.

Check Digit Verification of cas no

The CAS Registry Mumber 957205-14-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,7,2,0 and 5 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 957205-14:
(8*9)+(7*5)+(6*7)+(5*2)+(4*0)+(3*5)+(2*1)+(1*4)=180
180 % 10 = 0
So 957205-14-0 is a valid CAS Registry Number.

957205-14-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Bromo-peg5-alcohol

1.2 Other means of identification

Product number -
Other names Bromo-peg5-alcohol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:957205-14-0 SDS

957205-14-0Downstream Products

957205-14-0Relevant articles and documents

BIHETEROCYCLIC COMPOUND

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Paragraph 1172-1174, (2019/02/01)

The present invention provides a compound of formula (1) and a pharmaceutical composition comprising the compound useful as a nerve regeneration promoter wherein R1-L- is R1—OC(O)—, or the like, R1 is hydrogen atom, optionally-substituted C1-6 alkyl group, optionally-substituted 3- to 8-membered cycloalkyl group, or the like, R2 is hydrogen atom or the like, Ring A is formula (2) or formula (3) wherein R3 is hydrogen atom, optionally-substituted C1-6 alkyl group, or the like, the part of X, Y, and Z is X═Y—Z, X—Y═Z, or X—Y—Z, X is nitrogen atom, NR4 (R4 is hydrogen atom, optionally-substituted C1-6 alkyl group, or the like), or the like, Y is carbon atom or the like, and Z is carbon atom, nitrogen atom or the like.

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