![7,7-DICHLOROBICYCLO[3.2.0]HEPT-2-EN-6-ONE](http://file1.lookchem.com/cas/reactions/2021/06/28/2045059.png)
Relevant articles and documents
The Synthesis and Structure of a Cyclobutane Analogue of Glutamic Acid with an Acetic Acid Side Chain
Allan, Robin D. Apostopoulos, Christine Hambley, Trevor W.
A synthetic route involving a hydantoin derivative of bicyclo<3.2.0>hept-2-ene has been investigated for the preparation of neurotransmitter analogues containing an additional acetic acid substituent on the cyclobutane ring of the potent NMDA receptor agonist trans-1-aminocyclobutane-1,3-dicarboxylic acid.X-Ray analysis showed that the major cyclobutane amino acid produced had the 2-acetic acid and 3-carboxylic acid substituents in the trans-orientation as a result of epimerization during hydantoin hydrolysis.
Specifically Deuteriated Bicyclo<3.2.0>hepta-2,6-dienes
Baldwin, John E. Belfield, Kevin D.
An efficient synthetic route from the dichloroketene/cyclopentadiene adduct to bicyclo<3.2.0>hepta-2,6-diene has been developed and adapted to prepare deuteriated analogues of this diene labeled specifically at C1-C5, C6, or C7, or any combination of these possibilities.
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