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β-Lapachone

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Name

β-Lapachone

EINECS N/A
CAS No. 4707-32-8 Density 1.25g/cm3
PSA 43.37000 LogP 2.75210
Solubility N/A Melting Point >110oC (dec.)
Formula C15H14O3 Boiling Point 381.4°C at 760 mmHg
Molecular Weight 242.274 Flash Point 169.7°C
Transport Information N/A Appearance N/A
Safety Mutation data reported. When heated to decomposition it emits acrid smoke and irritating vapors. Risk Codes N/A
Molecular Structure Molecular Structure of 4707-32-8 (BETA-LAPACHONE) Hazard Symbols N/A
Synonyms

beta-lapachone;3,4-Dihydro-2,2-dimethyl-2H-naphtho(1,2-b)pyran-5,6-dione;|A-lapachone;3,4-dihydro-2,2-dimethyl-2H-naphthol[1,2-b]-pyran-5,6-dione;2,2-dimethyl-3,4-dihydrobenzo[h]chromene-5,6-dione;

Article Data 74

β-Lapachone Chemical Properties

IUPAC Name: 2,2-dimethyl-3,4-dihydrobenzo[h]chromene-5,6-dione 
Molecular Formula: C15H14O3
Molecular Weight: 242.29
Density: 1.25 g/cm3 
Melting Point: 155-156°C 
Flash Point: 169.7 °C
Boiling Point: 381.4 °C at 760 mmHg
Freely Rotating Bonds: 0
Polar Surface Area: 43.37 Å2
Index of Refraction: 1.595
Molar Refractivity: 65.76 cm3
Molar Volume: 193.5 cm3
Polarizability: 26.07 ×10-24 cm3
Surface Tension: 48.4 dyne/cm
Enthalpy of Vaporization: 62.97 kJ/mol
Vapour Pressure: 5.09E-06 mmHg at 25°C 
Storage temperature: -20 °C
The Cas Register Number  of β-Lapachone is 4707-32-8.The chemical synonyms of β-Lapachone (CAS NO.4707-32-8) are β-Lapachone ; 2,2-Dimethyl-3,4,5,10-tetrahydro-2H-naphtho[2,3-b]pyran-5,10-dione ; 3,4-Dihydro-2,2-dimethyl-2H-naphtho[2,3-b]pyran-5,10-dione .Product categories of β-Lapachone (CAS NO.4707-32-8) are DNA Repair Regulators Cancer Research ; Gene RegulationEnzyme Inhibitors by Enzyme ; Topoisomerase I ; Apoptosis and Cell Cycle ; Chemopreventive Agents ; DNA metabolism . The molecular structure of β-Lapachone (CAS NO.4707-32-8) is.

β-Lapachone Uses

 β-Lapachone (CAS NO.4707-32-8) is used in organic synthesis.

β-Lapachone Toxicity Data With Reference

1.    

dnd-ham-ovr 40 µmol/L

    MUREAV    Mutation Research. 401 (1998),55.
2.    

cyt-ham-ovr 2 µmol/L

    MUREAV    Mutation Research. 288 (1993),263.
3.    

sce-ham-ovr 1 µmol/L

    MUREAV    Mutation Research. 288 (1993),263.

β-Lapachone Safety Profile

Mutation data reported. When heated to decomposition it emits acrid smoke and irritating vapors.
WGK Germany: 3
RTECS: QL6127400

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