3663-20-5

Basic information

• Product Name: N1-(4-BUTYLPHENYL)ACETAMIDE
• Synonyms: 4-BUTYLACETANILIDE;N1-(4-BUTYLPHENYL)ACETAMIDE;4-N-BUTYLACETANILIDE;N-(4-butylphenyl)acetamide
• CAS NO: 3663-20-5
• Molecular Formula: C₁₂H₁₇NO
• Molecular Weight: 191.27
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 3663-20-5.mol
• Article Data: 13

Chemical Properties

• Melting Point: 107 °C
• Boiling Point: 349.6 °C at 760 mmHg
• Flash Point: 208.8 °C
• Appearance: /
• Density: 1.015 g/cm³
• Vapor Pressure: 4.65E-05mmHg at 25°C
• Refractive Index: 1.542
• CAS DataBase Reference: N1-(4-BUTYLPHENYL)ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N1-(4-BUTYLPHENYL)ACETAMIDE(3663-20-5)
• EPA Substance Registry System: N1-(4-BUTYLPHENYL)ACETAMIDE(3663-20-5)

Safety Data

• Hazard Codes: Xn:Harmful
• Statements: R22:Harmful if swallowed.
• Hazardous Substances Data: 3663-20-5(Hazardous Substances Data)

Usage

Description

N1-(4-BUTYLPHENYL)ACETAMIDE, also known as N-(4-Butylphenyl)acetamide, is an organic chemical compound that is a derivative of acetamide and classified as an aromatic amide. It is recognized for its analgesic and anti-inflammatory properties and is commonly used as an intermediate in the synthesis of pharmaceutical compounds, as well as in research and development.

Uses

Used in Pharmaceutical Industry:
N1-(4-BUTYLPHENYL)ACETAMIDE is used as an intermediate in the synthesis of pharmaceutical compounds for its potential role in developing new pain-relieving medications.
Used in Research and Development:
N1-(4-BUTYLPHENYL)ACETAMIDE is used as a research compound to explore its analgesic and anti-inflammatory properties, contributing to the advancement of pharmaceutical science and medicine.
N1-(4-BUTYLPHENYL)ACETAMIDE is considered to be a stable and non-hazardous compound when handled and stored properly, which makes it a suitable candidate for use in various applications within the pharmaceutical and chemical industries.

InChI:InChI=1/C12H17NO/c1-3-4-5-11-6-8-12(9-7-11)13-10(2)14/h6-9H,3-5H2,1-2H3,(H,13,14)

Upstream product

• 104-13-2 4-Butylaniline 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 
• 37920-25-5 1-(4-butylphenyl)ethanone 
• 592-41-6 1-hexene 
• 622-50-4 4-Acetamido-1-iodobenzene 
• 79887-09-5 (4-butylphenyl)acetylene 
• 62-53-3 aniline 
• 1126-78-9 N-(n-butyl)aniline 
• 20651-75-6 1-butyl-4-nitro-benzene 

Downstream Products

• 3663-21-6 N-(4-butyl-2-nitrophenyl)acetamide 
• 3663-24-9 5-n-butyl-1H-benzotriazole 
• 53977-28-9 6-butyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid 
• 104-13-2 4-Butylaniline 
• 1462270-82-1 2-acetamido-5-butylphenyl 4-chlorobenzoate 
• 1620-30-0 diphenyl(pyridin-4-yl)methanol 
• 1311382-56-5 5-butyl-2-(3-(4-(2-methoxyphenyl)piperazine-1-carbonyl)phenylsulfonamido)benzoic acid 
• 1311383-37-5 methyl 5-butyl-2-(3-(4-(2-methoxyphenyl)piperazine-1-carbonyl)phenylsulfonamido)benzoate 
• 1311383-36-4 3-(N-(4-butyl-2-(methoxycarbonyl)phenyl)sulfamoyl)benzoic acid 
• 1183950-19-7 methyl 2-amino-5-butylbenzoate 
• 1311383-35-3 N-(4-butyl-2-cyanophenyl)acetamide 
• 143359-99-3 N-(2-bromo-4-butylphenyl)acetamide 
• 18331-73-2 2-amino-5-butylbenzoic acid 
• 1259475-06-3 (E)-butyl 3-(2-acetamido-5-butylphenyl)acrylate 

Relevant articles and documents

Efficient nitriding reagent and application thereof

The invention discloses an efficient nitriding reagent and application thereof, wherein the nitriding reagent comprises nitrogen oxide, an active agent, a reducing agent and an organic solvent. By applying the nitriding reagent, nitrogen-containing compounds such as amide, nitrile and the like can be produced, and the method is simple in condition, low in waste discharge amount and simple in reaction equipment.

Visible-Light-Induced Nickel-Catalyzed Cross-Coupling with Alkylzirconocenes from Unactivated Alkenes

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Efficient Heterogeneous Gold(I)-Catalyzed Direct C(sp2)–C(sp) Bond Functionalization of Arylalkynes through a Nitrogenation Process to Amides

The first heterogeneous gold(I)-catalyzed direct C(sp2)–C(sp) bond functionalization of arylalkynes through a nitrogenation process to amides has been achieved by using an ordered mesoporous silica (MCM-41)-immobilized phosphine gold(I) complex [MCM-41-PPh3-AuCl] as catalyst and silver carbonate (Ag2CO3) as cocatalyst with trimethylsilyl azide (TMSN3) as a nitrogen source, yielding a variety of amides in moderate to excellent yields under mild conditions. This heterogeneous phosphine gold(I) complex shows the same turnover numbers as the homogeneous chloro(triphenylphosphine)gold(I) (Ph3PAuCl) and can easily be recovered by simple filtration of the reaction solution and recycled at least eight times without significant loss of activity, providing a novel, efficient, practical and economic method for the synthesis of amides from alkynes. (Figure presented.).