628-67-1 Usage
Description
1,4-DIACETOXYBUTANE, also known as butane-1,4-diol diacetate, is an acetate ester derived from the formal condensation of the two hydroxy groups of butane-1,4-diol with two molecules of acetic acid. It is a colorless liquid with a sweet, fruity odor and is soluble in water and most organic solvents.
Uses
Used in Pharmaceutical Industry:
1,4-DIACETOXYBUTANE is used as an intermediate in the synthesis of various pharmaceutical compounds, such as antibiotics, anti-inflammatory drugs, and antidepressants. Its ability to form esters with hydroxyl groups makes it a versatile building block in the development of new drugs.
Used in Flavor and Fragrance Industry:
1,4-DIACETOXYBUTANE is used as a flavoring agent and fragrance ingredient in the food, beverage, and cosmetics industries. Its sweet, fruity aroma adds a pleasant scent and taste to various products.
Used in Chemical Synthesis:
1,4-DIACETOXYBUTANE is used as a reagent and solvent in various chemical reactions, such as esterification, transesterification, and acylation. Its ability to dissolve a wide range of compounds makes it a useful solvent for many organic reactions.
Used in Research and Development:
1,4-DIACETOXYBUTANE is used as a research compound in the study of organic chemistry, biochemistry, and materials science. Its unique properties and reactivity make it an interesting subject for scientific investigation and the development of new applications.
Check Digit Verification of cas no
The CAS Registry Mumber 628-67-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 8 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 628-67:
(5*6)+(4*2)+(3*8)+(2*6)+(1*7)=81
81 % 10 = 1
So 628-67-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H14O4/c1-7(9)11-5-3-4-6-12-8(2)10/h3-6H2,1-2H3
628-67-1Relevant articles and documents
Rhakmankulov et al.
, (1976)
Preparation method of 1,4-butanediol and dicarboxylic acid ester thereof
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Paragraph 0032-0051; 0056; 0058, (2019/10/01)
The invention relates to a preparation method of 1,4-butanediol and a dicarboxylic acid ester thereof. Specifically, the preparation method of 1,4-butanediol and the dicarboxylic acid ester thereof comprises the following steps: performing hydrodecarbonylation esterification ring-opening on a furoic acid compound, a trifluoromethanesulfonate, a hydrogenation catalyst in a carboxylic acid solvent to obtain a 1,4-butanediol dicarboxylic acid ester. The method has the characteristics of simple process, easy purification, high yield, green safety, and the like, and is suitable for large-scale industrial production.
Lipase-mediated selective acetylation of primary alcohols in ethyl acetate
de Souza, Ernane C.,Romero-Ortega, Moises,Olivo, Horacio F.
supporting information, p. 287 - 290 (2017/12/29)
An environmental friendly process to selectively acetylate primary alcohols was demonstrated. The esterification process consists of treatment of a primary alcohol in the presence of immobilized C. antarctica lipase (Novozyme-435) in ethyl acetate at room temperature. Primary alcohols were acetylated in the presence of secondary alcohols and phenols.