131860-33-8Relevant articles and documents
AN IMPROVED PROCESS FOR PREPARATION OF METHYL (2E)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE
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Page/Page column 8, (2021/02/12)
The present invention relates to an improved processses for synthesizing preparing substituted cyanophenoxy-pyrimidinyloxy-phenyl acrylate derivatives. The present invention specifically relates to an improved process for the preparation of methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate having the following Formula I.
MENUFCACTURING METHOD OF AZOXYSTROBIN
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Paragraph 0050-0060, (2021/03/09)
MCMA ((E)- Methyl methyl methyl (2- ((6-chloropyrimidin-4-yl) oxy) phenyl).3 - methoxyacrylate). DABCO (1, 4-diazabicyclo [2.2.2] octane) and 2 - CP (2-cyanophenol) are mixed and fed into a reactor (z) by mixing into azoxystobin a continuous reactor and introducing them into a reactor.
METHOD FOR PREPARING AZOXYSTROBIN
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Paragraph 0018-0020; 0038-0041, (2020/06/15)
A method for preparing azoxystrobin comprises the following steps: (a) mixing methyl (E)-2-[2-(6-chloropyrimidin-4-yloxy)phenyl]-3-methoxyacrylate, 2-cyanophenol, potassium carbonate, and 10-80 mol % of 1-methylpyrrolidine as a catalyst in an aprotic solvent to form a basic mixture, and reacting the basic mixture for 2-5 hrs at a temperature of 60-120° C.; and (b) subjecting the basic mixture after reaction in Step (a) to a first distillation under a reduced pressure of 80-120 torr at 70-80° C., to obtain azoxystrobin.