913846-53-4Relevant articles and documents
PROCESS FOR PREPARATION OF AZOXYSTROBIN AND INTERMEDIATES THEREOF
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Page/Page column 33-32; 34-36, (2020/10/27)
The present invention relates to a process for preparation of strobilurin compound, azoxystrobin and its intermediates using a catalyst selected from 1,8-Diazabicyclo[5.4.0]undec-7-ene or 1,5-Diazabicyclo[4.3.0]non-5-ene, salts thereof, or derivatives thereof.
A process for preparing a azoxystrobin or intermediate catalyst and preparation method (by machine translation)
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Paragraph 0037, (2019/06/07)
The invention relates to a process for the preparation of azoxystrobin or intermediate catalyst, containing 1 - azabicyclo [2, 2, 2] octane structure on a series of compounds introduced into the amino or substituted amino, form the formula 10 structure shown or a salt thereof; the invention also relates to processes for preparing azoxystrobin or intermediates thereof, the present invention provides catalyst and preparation method, with process is easy to control, short reaction time, the conversion is high, and low energy consumption, and is suitable for large-scale industrial production. (by machine translation)
A new high-yield preparation of azoxystrobin method (by machine translation)
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Paragraph 0021; 0022; 0023; 0031, (2018/07/10)
The invention relates to a new method for high yield preparation of azoxystrobin, the reverse two-step etherification reaction synthesis azoxystrobin, specifically comprises the following steps: (1) by the O-hydroxy nitrile (compound B) and 4, 6 - two chlorine pyrimidine (compound C) in presence of catalyst first etherification reaction to obtain 4 - chloro - 6 - (2 - cyano-phenoxy) - pyrimidine (compound D); (2) by compound with D (E)- 3 - methoxy - 2 - (2 - hydroxy-phenyl) - acrylic acid methyl ester (compound E) in presence of catalyst and then carry on the etherification reaction to obtain azoxystrobin; two-step etherification reaction using the same kind of catalyst (compound F). Compared with the prior art, the method of the invention can improve the total yield to 80 - 85%. (by machine translation)