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1,7-Dihydroxynaphthalene

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Name

1,7-Dihydroxynaphthalene

EINECS 209-383-0
CAS No. 575-38-2 Density 1.33 g/cm3
PSA 40.46000 LogP 2.25100
Solubility Slightly soluble in water. Melting Point 178-182 °C
Formula C10H8O2 Boiling Point 375.4 °C at 760 mmHg
Molecular Weight 160.172 Flash Point 193.5 °C
Transport Information N/A Appearance Yellowish to white powder
Safety 26-36-37/39-36/37 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 575-38-2 (1,7-Dihydroxynaphthalene) Hazard Symbols IrritantXi
Synonyms

1,7-Dihydroxynaphthalene;C.I. 76635;NC 002;NSC 62686;

Article Data 13

1,7-Dihydroxynaphthalene Synthetic route

51850-49-8

1,7-diacetoxynaphthalene

A

575-38-2

1,7-Dihydroxynaphthalene

B

7-hydroxynaphthalen-1-yl acetate

C

7-acetoxy-1-hydroxynaphthalene

Conditions
ConditionsYield
With lipase of Pseudomonas sp; water In various solvent(s) at 25℃; for 0.6h; Hydrolysis; deacetylation;A n/a
B n/a
C 78%
135-19-3

β-naphthol

A

581-43-1

2,6-Dihydroxynaphthalene

B

575-38-2

1,7-Dihydroxynaphthalene

C

575-44-0

1,6-dihydroxynaphthalene

D

582-17-2

2,7-Dihydroxynaphthalene

Conditions
ConditionsYield
With dihydrogen peroxide; hydrogen fluoride; antimony pentafluoride at -40℃; for 0.25h; Mechanism; Product distribution;A 25.5%
B 29%
C 11%
D 3.5%
With dihydrogen peroxide; hydrogen fluoride; antimony pentafluoride at -40℃; for 0.25h;A 25.5%
B 29%
C 11%
D 3.5%
90-15-3

α-naphthol

A

575-38-2

1,7-Dihydroxynaphthalene

B

83-56-7

1,5-dihydroxynaphthalene

Conditions
ConditionsYield
With dihydrogen peroxide; hydrogen fluoride; antimony pentafluoride at -20℃; for 0.5h; Mechanism; Product distribution;A 17.5%
B 25.5%
With dihydrogen peroxide; hydrogen fluoride; antimony pentafluoride at -20℃; for 0.5h;A 17.5%
B 25.5%
19061-33-7

6-methoxy-1,4-dihydro-1,4-epoxidonaphthalene

575-38-2

1,7-Dihydroxynaphthalene

Conditions
ConditionsYield
With sodium hydride; ethanethiol In N,N-dimethyl-formamide at 130℃; for 7.5h;23%
90-51-7

6-amino-4-hydroxy-2-naphthalenesulfonic acid

575-38-2

1,7-Dihydroxynaphthalene

Conditions
ConditionsYield
With sulfuric acid at 200℃;
With hydrogenchloride at 200℃;
With phosphoric acid at 200℃;
With formic acid at 200℃;
132-57-0

7-hydroxy-naphthalene-1-sulfonic acid

575-38-2

1,7-Dihydroxynaphthalene

Conditions
ConditionsYield
With potassium hydroxide at 245 - 255℃; durch Verschmelzen;
With potassium hydroxide
119-28-8

8-amino-2-naphthalenesulfonic acid

furan-2,3,5(4H)-trione pyridine (1:1)

A

575-38-2

1,7-Dihydroxynaphthalene

B

118-46-7

8-amino-2-naphthol

C

20191-62-2

8-hydroxy-naphthalene-2-sulfonic acid

Conditions
ConditionsYield
at 260℃; unter Druck;
90-40-4

2-amino-8-hydroxy-naphthalene-3,6-disulphonic acid

575-38-2

1,7-Dihydroxynaphthalene

Conditions
ConditionsYield
With sulfuric acid at 200℃;
With hydrogenchloride at 200℃;
With phosphoric acid at 200℃;
With formic acid at 200℃;
86699-99-2

1,7-dihydroxy-2-naphthoic acid

575-38-2

1,7-Dihydroxynaphthalene

Conditions
ConditionsYield
With aniline
135-19-3

β-naphthol

A

581-43-1

2,6-Dihydroxynaphthalene

B

575-38-2

1,7-Dihydroxynaphthalene

Conditions
ConditionsYield
With hydrogen fluoride; boron trifluoride; dihydrogen peroxide at -50℃; for 0.5h; Mechanism; Product distribution; other naphthol, other temp.;

1,7-Dihydroxynaphthalene Chemical Properties

Chemical Name: 1,7-Dihydroxynaphthalene
IUPAC NAME: naphthalene-1,7-diol
CAS No.: 575-38-2
EINECS: 209-383-0
RTECS: QJ4746666
RTECS Class:Mutagen
Molecular Formula: C10H8O2
Molecular Weight: 160.17 g/mol
Melting Point: 180-184 °C(lit.)
Density: 1.33 g/cm3 
Flash Point: 193.5 °C 
Boiling Point: 375.4 °C at 760 mmHg
 1,7-NAPHTHALENEDIOL (575-38-2) is stable under normal temperatures and pressures.but incompatible with strong oxidizing agents.Following is the structure:

                         
The chemical synonymous of 1,7-NAPHTHALENEDIOL (575-38-2) are c.i.76635 ; 1,7-DIHYDROXYNAPHTHALENE ; 1,7-NAPHTHALENEDIOL ; naphthalene-1,7-diol ; 1,7-Napthalenediol ; 1,7-NAPHTHALENEDIOL 97% ; 1,7-DihydroxylNaphthalene ; 1,7-Dihydroxynaphthalin

1,7-Dihydroxynaphthalene Uses

 1,7-NAPHTHALENEDIOL (575-38-2) is mainly used as a pharmaceutical intermediate.

1,7-Dihydroxynaphthalene Production

Product Categories about 1,7-NAPHTHALENEDIOL (575-38-2) are Intermediates of Dyes and Pigments ; FINE Chemical & INTERMEDIATES ; Naphthalene derivatives

1,7-Dihydroxynaphthalene Toxicity Data With Reference

1.   

mic-sat 1600 nmol/plate

   MUREAV    Mutation Research. 371 (1996),293.

1,7-Dihydroxynaphthalene Safety Profile

Mutation data reported. When heated to decomposition it emits acrid smoke and irritating vapors.
Hazard Codes:
    Xn: Harmful
Risk Statements about 1,7-NAPHTHALENEDIOL (575-38-2):
    R22 Harmful if swallowed. 
    R36/37/38 Irritating to eyes, respiratory system and skin. 
Safety Statements about 1,7-NAPHTHALENEDIOL (575-38-2):
    S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
    S37/39 Wear suitable gloves and eye/face protection. 

1,7-Dihydroxynaphthalene Specification

1. Storage: Store in a cool, dry place. Store in a tightly closed container.
2. Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
3. Personal Protection: Compatible chemical-resistant gloves. Chemical safety goggles.
4. Fire Fighting: Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
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