IUPAC Name: 4-(chloromethyl)-1,3-thiazol-2-amine hydrochloride CAS Registry Number 59608-97-8  2-Thiazolamine, 4-(chloromethyl)-, monohydrochloride ; NSC 56821 ; 2-Thiazolamine, 4-(chloromethyl)-, hydrochloride (1:1) ; 2-Amino-4-(Chloromethy)thiazole HCl ; 2-Amino-4-(chloromethyl)-1,3-thiazole hydrochloride . It is a kind of thiazole.

The 2-Amino-4-chloromethythiazole hydrochloride can be obtained by thiourea and 1,3-dichloro-propan-2-one in the acetone at ambient temperature. The reaction time is 12 hours and the yield is 71.5 %.
 

The 2-Amino-4-chloromethythiazole hydrochloride can be used to synthesize other chemicals. For example: it can react with acetic acid anhydride to get N-(4-chloromethyl-thiazol-2-yl)-acetamide ; it reacts with thiocyanic acid; potassium salt to get 4-isothiocyanatomethyl-thiazol-2-ylamine ; it reacts with 5-nitro-3-piperidin-4-yl-1H-indole to get 4-[4-(5-nitro-1H-indol-3-yl)-piperidin-1-ylmethyl]-thiazol-2-ylamine ; it reacts with isobutyric acid anhydride to get N-(4-chloromethyl-thiazol-2-yl)-isobutyramide ; it reacts with trifluoroacetic acid anhydride to get N-(4-chloromethyl-thiazol-2-yl)-2,2,2-trifluoro-acetamide ; it reacts with carbonochloridic acid methyl ester to get (4-chloromethyl-thiazol-2-yl)-carbamic acid methyl ester ; it reacts with 4-methoxy-benzoic acid-anhydride to get N-(4-chloromethyl-thiazol-2-yl)-4-methoxy-benzamide .

The other characteristics of this product can be summarized as: (1)H bond acceptors: 2 ; (2)H bond donors: 2 ; (3)Freely Rotating Bonds: 1 ; (4)Enthalpy of Vaporization: 53.97 kJ/mol ; (5)Vapour Pressure: 0.00118 mmHg at 25°C. People can use the following data to convert to the molecule structure. SMILES: Cl.ClCc1nc(sc1)N; InChI: InChI=1/C4H5ClN2S.ClH/c5-1-3-2-8-4(6)7-3;/h2H,1H2,(H2,6,7);1H.