Welcome to LookChem.com Sign In | Join Free Post buying lead Chemical Tools
Home > Hot Product_List > 4-Methylsalicylic Acid

Basic information

  • Name:
  • Benzoicacid, 2-hydroxy-4-methyl-

  • Superlist Name:
  • 4-Methylsalicylic acid
  • CAS No.:
  • 50-85-1

  • Molecular Structure:
  • Formula:
  • C8H8O3
  • Molecular Weight:
  • 152.15
  • Synonyms:
  • 2,4-Cresoticacid (8CI);2-Hydroxy-4-methylbenzoic acid;2-Hydroxy-p-toluic acid;4-Methyl-2-hydroxybenzoic acid;NSC 16634;m-Cresoticacid;m-Cresotinic acid;m-Homosalicylic acid;p-Methylsalicylic acid;g-Cresoticacid;
  • EINECS:
  • 200-068-3
  • Density:
  • 1.304 g/cm3
  • Melting Point:
  • 173-177 °C(lit.)
  • Boiling Point:
  • 315.2 °C at 760 mmHg
  • Flash Point:
  • 158.6 °C
  • Appearance:
  • white to greyish-beige powder
  • Hazard Symbols:
  • HarmfulXn, IrritantXi
  • Risk Codes:
  • 22-36/37/38
  • Safety Description:
  • 26-37/39 Details

Famous Chemical Enterprises

  • Livzon
  • Total
  • Shell
  • Dupont
  • Exxonmobil
  • Akzonobel
  • Basf
  • Bayer
  • BP

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Specification

The IUPAC name of 4-Methylsalicylic Acid is 2-hydroxy-4-methylbenzoic acid. With the CAS registry number 50-85-1, it is also named as 2-Hydroxy-p-toluic acid; gamma-Cresotic acid. The product's categories are aromatic carboxylic acids, amides and anilides, anhydrides & salts. It is white to greyish-beige powder.  

The other characteristics of this product can be summarized as: (1)ACD/LogP: 2.52; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.42; (4)ACD/LogD (pH 7.4): -0.63; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 2; (12)Index of Refraction: 1.599; (13)Molar Refractivity: 39.88 cm3; (14)Molar Volume: 116.6 cm3; (15)Polarizability: 15.81×10-24 cm3; (16)Surface Tension: 58 dyne/cm; (17)Enthalpy of Vaporization: 58.75 kJ/mol; (18)Vapour Pressure: 0.000188 mmHg at 25°C; (19)Rotatable Bond Count: 1; (20)Tautomer Count: 12; (21)Exact Mass: 152.047344; (22)MonoIsotopic Mass: 152.047344; (23)Topological Polar Surface Area: 57.5; (24)Heavy Atom Count: 11.
 
Uses of 4-Methylsalicylic Acid: 1.It reacts with methanol to get 2-hydroxy-4-methyl-benzoic acid methyl ester. This reaction needs reagent H2SO4 at temperature of 70 °C.



2.It also reacts with 2-hydroxyamino-phenol to obtain 2-benzooxazol-2-yl-5-methyl-phenol. This reaction needs reagent polyphosphoric acid at temperature of 150-180 °C. The reaction time is 8 hours. The yield is 27%.

When you are using this chemical, please be cautious about it as the following:
It is harmful if swallowed. And it is irritating to eyes, respiratory system and skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection. 

People can use the following data to convert to the molecule structure.
1.SMILES: O=C(O)c1ccc(cc1O)C;
2. InChI: InChI=1/C8H8O3/c1-5-2-3-6(8(10)11)7(9)4-5/h2-4,9H,1H3,(H,10,11).

The following is the toxicity data which has been tested. 

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 1800mg/kg (1800mg/kg)   Acta Pharmaceutica Suecica. Vol. 7, Pg. 289, 1970.

Please post your buying leads
so that our qualified suppliers will soon contact you!

©2008 LookChem.com,License:ICP NO.:Zhejiang10014259

[Hangzhou]86-571-85317600,85317603,85317620