Basic Information | Post buying leads | Suppliers | Cas Database |
Name |
4-Quinolinol, 8-fluoro-2-methyl- |
EINECS | N/A |
CAS No. | 5288-22-2 | Density | 1.305 g/cm3 |
PSA | N/A | LogP | N/A |
Solubility | N/A | Melting Point |
N/A |
Formula | C10H8FNO | Boiling Point | 316.7 °C at 760 mmHg |
Molecular Weight | 177.18 | Flash Point | 145.3 °C |
Transport Information | N/A | Appearance | N/A |
Safety | 26-39 | Risk Codes | 22-41 |
Molecular Structure | Hazard Symbols | Xi | |
Synonyms |
8-Fluoro-2-methyl-4-quinolinol;8-Fluoro-2-methylquinolin-4-ol;8-Fluoro-4-hydroxyquinaldine;8-Fluoro-4-hydroxy-2-methylquinoline; |
Article Data | 4 |
The 4-Quinolinol, 8-fluoro-2-methyl-, with the CAS registry number 5288-22-2, is also known as 8-Fluoro-2-methyl-4-quinolinol. This chemical's molecular formula is C10H8FNO and molecular weight is 177.18. What's more, its systematic name is 8-Fluoro-2-methylquinolin-4-ol. Besides, the product should be stored at room temperature.
Physical properties of 4-Quinolinol, 8-fluoro-2-methyl- are: (1)ACD/LogP: 3.01; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.11; (4)ACD/LogD (pH 7.4): 2.1; (5)ACD/BCF (pH 5.5): 14.47; (6)ACD/BCF (pH 7.4): 13.98; (7)ACD/KOC (pH 5.5): 130.75; (8)ACD/KOC (pH 7.4): 126.32; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 33.12 Å2; (13)Index of Refraction: 1.64; (14)Molar Refractivity: 48.88 cm3; (15)Molar Volume: 135.6 cm3; (16)Polarizability: 19.38×10-24 cm3; (17)Surface Tension: 52.3 dyne/cm; (18)Density: 1.305 g/cm3; (19)Flash Point: 145.3 °C; (20)Enthalpy of Vaporization: 58.03 kJ/mol; (21)Boiling Point: 316.7 °C at 760 mmHg; (22)Vapour Pressure: 0.000218 mmHg at 25°C.
Preparation: this chemical can be prepared by acetoacetic acid ethyl ester and 2-fluoro-aniline at the temperature of 140 °C. This reaction will need reagent polyphosphoric acid with the reaction time of 2 hours. The yield is about 73.5%.
Uses of 4-Quinolinol, 8-fluoro-2-methyl-: it can be used to produce 8-fluoro-2-methyl-3-phenylazo-quinolin-4-ol at the temperature of 5 °C. It will need reagent NaOH and solvent H2O. The yield is about 73%.
You can still convert the following datas into molecular structure:
(1)Canonical SMILES: CC1=CC(=O)C2=C(N1)C(=CC=C2)F
(2)InChI: InChI=1S/C10H8FNO/c1-6-5-9(13)7-3-2-4-8(11)10(7)12-6/h2-5H,1H3,(H,12,13)
(3)InChIKey: LLUXFHIYAWGJGO-UHFFFAOYSA-N