Basic information
- Name:
1,4:5,8-Dimethanonaphthalene,1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8a-hexahydro-, (1R,4S,4aS,5S,8R,8aR)-rel-
- CAS No.:
309-00-2
- Molecular Structure:

- Formula:
- C12H8 Cl6
- Synonyms:
- 1,4:5,8-Dimethanonaphthalene,1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8a-hexahydro-, (1a,4a,4ab,5a,8a,8ab)-;1,4:5,8-Dimethanonaphthalene,1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8a-hexahydro-, endo,exo- (8CI);1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-1,4-endo-exo-5,8-dimethanonaphthalene;1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-endo-1,4-exo-5,8-dimethanonaphthalene;Aldocit;Aldrex 25;Aldrex 40;Aldrin;Andrex;Andrex 40;Compound 118;ENT15,949;HHDN;Kortofin;Octalene;SD 2794;Seedrin;Tatuzinho;
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Chemistry
Product Name: Aldrin
Molecular Structure:
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Molecular Formula: C12H8Cl6
Molecular Weight: 364.9099
Synonyms of Aldrin (CAS NO.309-00-2): 1,4:5,8-Dimethanonaphthalene, 1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8a-hexahydro-, endo,exo- ; 1,4:5,8-Dimethanonaphthalene, 1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8a-hexahydro-, (1alpha,4alpha,4abeta,5alpha,8alpha,8abeta)- ; Aldrin, liquid ; Aldrin, liquid [NA2762] [Poison] ; Aldrin, solid ; Aldrin, solid [NA2761] [Poison] ; NA2761 ; NA2762 ; RCRA waste no. P004
CAS NO: 309-00-2
Classification Code: Agricultural Chemical ; Human Data ; Insecticide ; Insecticides ; Mutation data ; Out-dated pesticide ; Pesticides ; Reproductive Effect ; Tumor data
Index of Refraction: 1.659
Molar Refractivity: 77.741 cm3
Molar Volume: 210.723 cm3
Surface Tension: 55.317 dyne/cm
Density: 1.732 g/cm3
Flash Point: 186.068 °C
Enthalpy of Vaporization: 60.886 kJ/mol
Boiling Point: 384.92 °C at 760 mmHg
History
Aldrin (CAS NO.309-00-2) is named after the German chemist Kurt Alder, one of the coinventors of this kind of reaction. An estimated 270 million kilograms of aldrin and related cyclodiene pesticides were produced between 1946 and 1976.
Uses
Aldrin (CAS NO.309-00-2) is an organochlorine insecticide that was widely used until the 1970's when it was banned in most countries.
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| bird - wild | LD50 | oral | 7200ug/kg (7.2mg/kg) | Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972. | |
| cat | LDLo | oral | 15mg/kg (15mg/kg) | LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA LIVER: FATTY LIVER DEGERATION KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Communicationes Veterinariae. Vol. 2, Pg. 71, 1958. |
| cat | LDLo | skin | 75mg/kg (75mg/kg) | LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA KIDNEY, URETER, AND BLADDER: OTHER CHANGES LIVER: FATTY LIVER DEGERATION | Communicationes Veterinariae. Vol. 2, Pg. 71, 1958. |
| chicken | LD50 | oral | 10mg/kg (10mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Journal of Economic Entomology. Vol. 45, Pg. 121, 1952. |
| child | LDLo | oral | 1250ug/kg (1.25mg/kg) | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 82, 1969. | |
| dog | LD50 | intraperitoneal | 1999mg/kg (1999mg/kg) | LIVER: LIVER FUNCTION TESTS IMPAIRED | Toxicology and Applied Pharmacology. Vol. 10, Pg. 119, 1967. |
| dog | LD50 | oral | 65mg/kg (65mg/kg) | Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 7, 1966. | |
| dog | LDLo | unreported | 95mg/kg (95mg/kg) | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 3, Pg. 64, 1951. | |
| duck | LD50 | oral | 520mg/kg (520mg/kg) | Down to Earth. Vol. 35, Pg. 25, 1979. | |
| guinea pig | LD50 | oral | 33mg/kg (33mg/kg) | Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 7, 1966. | |
| hamster | LD50 | oral | 100mg/kg (100mg/kg) | Teratology, The International Journal of Abnormal Development. Vol. 9, Pg. 11, 1974. | |
| human | TDLo | oral | 14mg/kg (14mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: EXCITEMENT GASTROINTESTINAL: NAUSEA OR VOMITING | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 82, 1969. |
| mammal (species unspecified) | LD50 | unreported | 40mg/kg (40mg/kg) | "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 62, 1971. | |
| mouse | LD50 | intracrebral | 4mg/kg (4mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Toxicology Letters. Vol. 60, Pg. 289, 1992. |
| mouse | LD50 | intraperitoneal | 50mg/kg (50mg/kg) | Soviet Genetics. English translation of GNKAA5. Vol. 2, Pg. 80, 1966. | |
| mouse | LD50 | intravenous | 21mg/kg (21mg/kg) | "Aldrin Dieldrin Endrin and Telodrin: An Epidemiological and Toxicological Study of Long-Ter Occupational Exposure," Jager, K.W., New York, Elsevier Science Pub. Co., 1970Vol. -, Pg. 52, 1970. | |
| mouse | LD50 | oral | 44mg/kg (44mg/kg) | Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 12, 1978. | |
| pigeon | LD50 | oral | 56200ug/kg (56.2mg/kg) | ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979. | |
| quail | LD50 | oral | 42100ug/kg (42.1mg/kg) | ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979. | |
| rabbit | LD50 | oral | 50mg/kg (50mg/kg) | Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 7, 1966. | |
| rabbit | LD50 | skin | 15mg/kg (15mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Journal of Economic Entomology. Vol. 46, Pg. 702, 1953. |
| rabbit | LDLo | subcutaneous | 100mg/kg (100mg/kg) | "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 73, 1982. | |
| rat | LCLo | inhalation | 5800ug/m3/4H (5.8mg/m3) | "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 73, 1982. | |
| rat | LD50 | intraperitoneal | 150mg/kg (150mg/kg) | Toxicology and Applied Pharmacology. Vol. 11, Pg. 302, 1967. | |
| rat | LD50 | oral | 39mg/kg (39mg/kg) | Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 12, 1978. | |
| rat | LD50 | skin | 98mg/kg (98mg/kg) | Toxicology and Applied Pharmacology. Vol. 14, Pg. 515, 1969. | |
| rat | LD50 | subcutaneous | 62mg/kg (62mg/kg) | "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 73, 1982. |
Safety Profile
Hazard Codes of Aldrin (CAS NO.309-00-2):
T,
N,
Xn,
F,
Xi
Risk Statements: 40-48-50/53-67-65-11-20/21/22-36/37/38-39-23/24/25
R40: Limited evidence of a carcinogenic effect.
R48: Danger of serious damage to health by prolonged exposure.
R50/53: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R67: Vapours may cause drowsiness and dizziness.
R65: Harmful: may cause lung damage if swallowed.
R11: Highly flammable.
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
R39: Danger of very serious irreversible effects.
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.
Safety Statements: 22-36/37-45-60-61-62-26-16-33-7
S22:Do not breathe dust.
S36/37:Wear suitable protective clothing and gloves.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S60: This material and its container must be disposed of as hazardous waste.
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
S62: If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S16: Keep away from sources of ignition.
S33: Take precautionary measures against static discharges.
S7: Keep container tightly closed.
RIDADR: 2761
RTECS: IO2100000
HazardClass: 6.1(a)
PackingGroup: II
Specification
Aldrin (CAS NO.309-00-2) has rat LD50 of 39 to 60 mg/kg (oral in rats).
This colourless solid was heavily used as a pesticide to treat seed and soil. Aldrin and related "cyclodiene" pesticides became notorious as persistent organic pollutants.
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