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Azacosterol dihydrochloride

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Name

Azacosterol dihydrochloride

EINECS N/A
CAS No. 1249-84-9 Density g/cm3
PSA 26.71000 LogP 6.16620
Solubility N/A Melting Point N/A
Formula C25H44 N2 O . 2 Cl H Boiling Point 490.6°Cat760mmHg
Molecular Weight 461.63 Flash Point 210.4°C
Transport Information N/A Appearance N/A
Safety Poison by ingestion and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and HCl. Risk Codes N/A
Molecular Structure Molecular Structure of 1249-84-9 (Azacosterol) Hazard Symbols N/A
Synonyms

Androst-5-en-3-ol,17-[[3-(dimethylamino)propyl]methylamino]-, dihydrochloride, (3b,17b)- (9CI); Androst-5-en-3b-ol, 17b-[[3-(dimethylamino)propyl]methylamino]-, dihydrochloride (7CI,8CI); 17b-[[3-(Dimethylamino)-propyl]methylamino]androst-5-en-3b-ol dihydrochloride;20,25-Diazacholesterol dihydrochloride; Azacosterol dihydrochloride;Azacosterol hydrochloride; DiazaCon; IMD 760; Ornitrol; SC 12937

 

Azacosterol dihydrochloride Chemical Properties

Molecular Structure of Azacosterol dihydrochloride (CAS NO. 1249-84-9):

IUPAC Name: (3S,8R,9S,10R,13S,14S,17S)-17-[3-(dimethylamino)propyl-methylamino]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol dihydrochloride
Empirical Formula: C25H46Cl2N2
Molecular Weight: 461.5515 
Flash Point: 210.4 °C 
Enthalpy of Vaporization: 87.23 kJ/mol 
Boiling Point: 490.6 °C at 760 mmHg 
Vapour Pressure: 1.1E-11 mmHg at 25°C 
Classification Code: Acaricide;Agricultural Chemical;Chemosterilant, avian;Insect attractant, repellent and chemosterilant;Mutation data;Reproductive Effect 

Azacosterol dihydrochloride Toxicity Data With Reference

1.    

oms-pgn-orl 600 mg/kg/10 D-I

    JRPFA4    Journal of Reproduction and Fertility. 15 (1968),145.
2.    

spm-pgn-orl 600 mg/kg/10 D-I

    JRPFA4    Journal of Reproduction and Fertility. 15 (1968),145.
3.    

ipr-rat TDLo:100 mg/kg (male 10 D pre):REP

    JOAND3    Journal of Andrology. 7 (1986),277.
4.    

orl-rat LD50:470 mg/kg

    85ARAE    Agricultural Chemicals, Books I, II, III, and IV 3 (1976/77),100.
5.    

ipr-rat LD50:60 mg/kg

    FMCHA2    Farm Chemicals Handbook .(Meister Publishing,Willoughy, OH.: )1983,C174.
6.    

orl-mus LD50:380 mg/kg

    FMCHA2    Farm Chemicals Handbook .(Meister Publishing,Willoughy, OH.: )1983,C174.
7.    

ipr-mus LD50:92 mg/kg

    FMCHA2    Farm Chemicals Handbook .(Meister Publishing,Willoughy, OH.: )1983,C174.

Azacosterol dihydrochloride Safety Profile

Poison by ingestion and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and HCl.

Azacosterol dihydrochloride Specification

 Azacosterol dihydrochloride ,its CAS number is 1249-84-9,it can be called (3b,17b)-17-((3-(Dimethylamino)propyl)methylamino)androst-5-en-3-ol Dihydrochloride ; (3beta,17beta)-17-{[3-(Dimethylamino)propyl](methyl)amino}androst-5-en-3-ol dihydrochloride ; 17b-((3-(Dimethylamino)-propyl)methylamino)androst-5-en-3b-ol Dihydrochloride ; 17beta-((3-(Dimethylamino)-propyl)methylamino)androst-5-en-3beta-ol dihydrochloride ; 20,25-Diazachlolestenol dihydrochloride ;androst-5-en-3-ol, 17-[[3-(dimethylamino)propyl]methylamino]-, (3beta,17beta)-, hydrochloride (1:2) and so on.

 Azacosterol dihydrochloride (CAS NO. 1249-84-9) is a high toxic substance,with flammability, burning will produce toxic fumes of nitrogen oxides and hydrogen chloride,so it should be stored in cool and dry environment,dry powder,foam,sand, carbon dioxide,water mist can be used if something urgent happened.

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