Basic Information | Post buying leads | Suppliers |
Name |
Beta-Amyloid (1-42) human |
EINECS | N/A |
CAS No. | 107761-42-2 | Density | N/A |
PSA | 1840.49000 | LogP | 1.35150 |
Solubility | N/A | Melting Point |
N/A |
Formula | C203H311N55O60S | Boiling Point | N/A |
Molecular Weight | 4514.04 | Flash Point | N/A |
Transport Information | N/A | Appearance | N/A |
Safety | 24/25 | Risk Codes | N/A |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
Amyloid b 1-42;Amyloid, b- (1-42);Ab1-42;abeta 1-42;Peptide b (human amyloid); |
The Molecular Structure of Beta-Amyloid (1-42) human (CAS NO.107761-42-2):
Molecular Formula: C203H311N55O60S
Molecular Weight: 4514.04
Product Categories: Peptide;Amyloid beta Protein Fragments;Amyloid β Protein FragmentsNeuropeptides;Alzheimers and Neurodegenerative Disease Research;Neurodegenerative Disease Peptides;β Amyloid Peptides;Amyloid beta-peptide and related;Signalling
Storage temp: −20°C
Solubility: insoluble in water, may be dissolved in any buffer with pH greater than 9
Synonyms: L-alpha-Aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-serylglycyl-L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valylglycyl-L-seryl-L-asparaginyl-L-lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-L-leucyl-L-methionyl-L-valylglycylglycyl-L-valyl-L-valyl-L-isoleucyl-L-alanine
WGK Germany: 3
This peptide is well suited to the quantitative determination of A 42 peptide. Alzheimer’s disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid peptide (A), a 40- to 43- amino-acid peptide cleaved from amyloid precursor protein by secretase (BACE) and a putative (gamma) secretase. Increased release of the ‘longer forms’ of A peptide, A 42 and A 43, which have a greater tendency to aggregate than A 40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alleles or may other, still undiscovered factors.