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Biuret

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Name

Biuret

EINECS 203-559-0
CAS No. 108-19-0 Density 1.432 g/cm3
PSA 98.21000 LogP 0.52490
Solubility Soluble in alcohol, very slightly soluble in ether Melting Point 186–189 °C(dec.)
Formula C2H5N3O2 Boiling Point 358.2 °C at 760 mmHg
Molecular Weight 103.081 Flash Point 170.4 °C
Transport Information N/A Appearance white crystal
Safety 26-36/37-36 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 108-19-0 (Biuret) Hazard Symbols IrritantXi
Synonyms

Allophanamide;Allophanic acid amide;Allophanimidic acid;Carbamylurea;Desmodeyn 75;Dicarbamylamine;Isobiuret;N 75;NSC 8020;Urea, (aminocarbonyl)-;Ureidoformamide;Imidodicarbonic diamide;

Article Data 147

Biuret Specification

The Biuret with CAS registry number of 108-19-0 is also known as Allophanic acid amide. The IUPAC name is Carbamoylurea. It belongs to product categories of General Protein Quantitation; Protein Quantitation; Quantitation Kits and Reagents. Its EINECS registry number is 203-559-0. In addition, the formula is C2H5N3O2 and the molecular weight is 103.08. This chemical is a white crystal and should be stored in cool, ventilate room away from strong oxidants, alkali and heat.

Physical properties about Biuret are: (1)ACD/LogP: -2.14; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): -2.14; (4)ACD/LogD (pH 7.4): -2.15; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1.63; (8)ACD/KOC (pH 7.4): 1.61; (9)#H bond acceptors: 5; (10)#H bond donors: 5; (11)#Freely Rotating Bonds: 0; (12)Index of Refraction: 1.524; (13)Molar Refractivity: 22.03 cm3; (14)Molar Volume: 71.9 cm3; (15)Surface Tension: 69.6 dyne/cm; (16)Density: 1.432 g/cm3; (17)Flash Point: 170.4 °C; (18)Enthalpy of Vaporization: 69.88 kJ/mol; (19)Boiling Point: 358.2 °C at 760 mmHg; (20)Vapour Pressure: 1.43E-06 mmHg at 25 °C.

Preparation of Biuret: it is prepared by heating urea and ammonia is expelled at the temperature.

2CO(NH2)2 → H2N-CO-NH-CO-NH2 + NH3

Uses of Biuret: it is used as pharmaceutical intermediate, growth hormone, blowing agent and paint. It is also used to produce 1-nitro-biuret. The reaction occurs with reagents 96% sulfuric acid, 70% nitric acid for 1.5 hours. The yield is about 47%.

Biuret is used to produce 1-nitro-biuret.

When you are using this chemical, please be cautious about it. As a chemical, it is irritating to eyes, respiratory system and skin. During using it, wear suitable protective clothing and gloves. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
1. Canonical SMILES: C(=O)(N)NC(=O)N
2. InChI: InChI=1S/C2H5N3O2/c3-1(6)5-2(4)7/h(H5,3,4,5,6,7)
3. InChIKey: OHJMTUPIZMNBFR-UHFFFAOYSA-N

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