One-pot diastereoselective synthesis of 2-acyl-4-nitrocyclohexanol derivatives in aqueous medium
The reaction of primary nitroalkanes with conjugated enones, in water and in the presence of K2CO3 as base, allows the synthesis of 2-acyl-4- nitrocyclohexanol derivatives in which the diastereoisomer (±)- (1S*,2R*,5R) is highly pred