- Identification of organic reaction products in the absence of additivity of chromatographic retention indices. Chloro derivatives of methyl-tert-butyl ketone
-
As a result of a joint interpretation of mass spectra and gas chromatographic retention indices more than ten products of free radical chlorination of methyl-tert-butyl ketone are identified. They contain from one to six chlorine atoms in the molecule and were not previously characterized either by mass spectrometric or chromatographic reference data. It is found that retention index increments corresponding to a gradual increase in the number of chlorine atoms in the molecule per unit are non-additive and vary in wide ranges (from 53 i.u. to 219 i.u.), which does not hinder the use of separate elements of additive schemes for the estimation of the indices of products of such non-regioselective reactions.
- Zenkevich,Eliseenkov,Kasatochkin
-
p. 505 - 514
(2013/07/26)
-
- Simple and efficient methods for selective preparation of α-mono or α,α-dichloro ketones and β-ketoesters by using DCDMH
-
New processes that can selectively prepare α-mono or α,α-dichloro ketones and β-ketoesters using 1,3-dichloro-5,5-dimethylhydantoin (DCDMH) are reported. Using silica gel as the catalyst and methanol as the solvent and heating for 1 h under reflux, α-monochlorinated products were selectively obtained in 86-98% yield. However using a deep eutectic solvent (choline chloride: p-TsOH = 1:1) as the solvent and stirring for 45 min at room temperature, α,α- dichlorinated products were selectively obtained in 86-95% yield.
- Chen, Zizhan,Zhou, Bin,Cai, Huihua,Zhu, Wei,Zou, Xinzhuo
-
experimental part
p. 275 - 278
(2010/04/22)
-
- Enantioselective synthesis of cyclic sulfamidates via Pd-catalyzed hydrogenation
-
Using Pd(CF3;CO2)2/(S,S)-f-binaphane as the catalyst, an efficient enantioselective synthesis of cyclic sulfamidates was developed via asymmetric hydrogenation of the corresponding cyclic imines in 2,2,2-trifluoroethanol at room temperature with high enantioselectivities (up to 99% ee).
- Wang, You-Qing,Yu, Chang-Bin,Wang, Da-Wei,Wang, Xiao-Bing,Zhou, Yong-Gui
-
supporting information; experimental part
p. 2071 - 2074
(2009/04/18)
-
- Selective halogenation of ketones
-
The present invention provides a process and apparatus for selectively halogenating a ketone of the formula (I) wherein R represents unsubstituted or halogen-substituted C1-C16-alkyl, or aryloxy, R1, R2 and R3 independently represent hydrogen, halogen, C1-C16-alkyl or aryl, the process involving heating the ketone to reflux in a reaction vessel such that the ketone vapor contacts a condensor attached to the reaction vessel and condenses, reacting the condensed ketone with halogen gas, and collecting the selectively halogenated ketone in the reaction vessel.
- -
-
-
- SYNTHESIS OF α-TELLUROKETONES
-
α-Telluroketones were prepared by reacting 4-methoxyphenyltellurium trichloride either with ketones or silyl enol ethers of ketones.The products upon pirolysis furnish α-chloroketones.
- Stefani, H. A.,Comasseto, J. V.,Petragnani, N.
-
p. 443 - 450
(2007/10/02)
-