cas 156755-35-0, 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-(phenylmethoxy)benzoic acid methyl ester

Articles about 156755-35-0Total 8 be found

PROCESS FOR THE PREPARATION OF FESOTERODINE OR ITS SALTS
The present invention relates to a process for the preparation of fesoterodine or its salts.
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(2013/04/13)

PROCESS FOR THE PREPARATION OF MUSCARINIC RECEPTOR ANTAGONIST
The present invention relates to novel and improved processes for the preparation of (r)-2-(3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenylisobutyrate represented by the following structural formula-1 and its pharmaceutically acceptable salts thereof.
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Page/Page column 59

(2012/08/07)

PROCESSES FOR THE PREPARATION OF FESOTERODINE
The invention relates to improved process for the preparation of fesoterodine and its pharmaceutically acceptable salt, specifically fesoterodine fumarate of formula (1). The invention relates to solid state forms of a novel salt of fesoterodine and process for the preparation thereof. The invention also relates to highly pure fesoterodine fumarate substantially free of impurity X at RRT 1.37. The invention also provides solid particles of pure fesoterodine fumarate wherein 90 volume-percent of the particles (D90) have a size of higher than 200 microns.
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Page/Page column 30

(2012/03/26)

IMPROVED PROCESS FOR DIPHENYLPROPYLAMINE DERIVATIVES
The present invention relates to an improved process for the preparation of biologically active diphenylpropylamine derivatives. The present invention specifically relates to an improved fesoterodine of formula (I) and its pharmaceutically acceptable salts.
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(2011/12/04)

SOLID STATE FORMS OF FESOTERODINE INTERMEDIATES
Provided herein are novel solid state forms of fesoterodine intermediates, (R)-4-benzyloxy-3-(3-diisopropylamino-1-phenylpropyl)-benzoic acid and (R)-[4-benzyloxy-3-(3-diisopropylamino-1-phenylpropyl)-phenyl]-methanol, and processes for their preparation thereof. The solid state intermediates are useful for preparing fesoterodine or a pharmaceutically acceptable salt thereof in high purity.
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(2011/06/19)

Process for the Preparation of Fesoterodine
Disclosed herein is an improved, commercially viable and industrially advantageous process for the preparation of Fesoterodine or a pharmaceutically acceptable salt thereof in high yield and purity. Disclosed also herein is an improved and industrially advantageous optical resolution method of racemic (±)-N,N-Diisopropyl-3-(2-benzyloxy-5-bromophenyl)-3-phenylpropylamine and use thereof for the preparation of Fesoterodine.
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Page/Page column 10

(2010/09/05)

ACCELERATED SYNTHESIS OF SUBSTITUTED HYDROXYMETHYL PHENOLS
This disclosure relates to process for the preparation of a compound of formula (I) wherein R is hydrogen, a straight or branched C1-C6 alkylcarbonyl group or a phenylcarbonyl group, or a salt thereof , comprising the following steps
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Page/Page column 17-18

(2008/06/13)

A shortened synthesis of substituted hydroxymethyl phenols
The present disclosure relates to a process for the preparation of 2-(3-diisopropylamino-1-phenylpropyl)-4-(hydroxymethyl)phenol or its phenolic monoesters or salts thereof, characterized by the steps of a) reacting a compound of formula (II) with a mixture of MeMgCl and Mg in a solvent, b) optionally reducing the temperature of the Grignard reagent to a lower temperature than in step a), and reacting the resulting Grignard reagent with an excess of a carbonate in a solvent, to obtain a compound of formula (III) wherein A is a C1-C6 alkyl group, and then further reacting the compound of formula (III) in a known manner to obtain the desired end product.
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Page/Page column 12-13

(2008/06/13)