156755-35-0

Basic information

• Product Name: 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-(phenylmethoxy)benzoic acid methyl ester
• Synonyms: 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-(phenylmethoxy)benzoic acid methyl ester;Benzoic acid, 3-[(1R)-3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-(phenylmethoxy)-, methyl ester;(R)-methyl 4-(benzyloxy)-3-(3-(diisopropylamino)-1-phenylpropyl)benzoate
• CAS NO: 156755-35-0
• Molecular Formula: C₃₀H₃₇NO₃
• Molecular Weight: 459.62
• Mol File: 156755-35-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 574.939 °C at 760 mmHg
• Flash Point: 301.512 °C
• Appearance: /
• Density: 1.063
• PKA: 10.60±0.28(Predicted)
• CAS DataBase Reference: 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-(phenylmethoxy)benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-(phenylmethoxy)benzoic acid methyl ester(156755-35-0)
• EPA Substance Registry System: 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-(phenylmethoxy)benzoic acid methyl ester(156755-35-0)

Safety Data

• Hazardous Substances Data: 156755-35-0(Hazardous Substances Data)

Upstream product

• 616-38-6 carbonic acid dimethyl ester 
• 67-56-1 methanol 
• 156755-33-8 (R)-4-(benzyloxy)-3-(3-(diisopropylamino)-1-phenylpropyl)benzoic acid hydrochloride 
• 950773-38-3 R-(-)-[3-(2-benzyloxy-5-bromophenyl)-3-phenylpropyl]diisopropylamine 
• 140-10-3 (E)-3-phenylacrylic acid 
• 106-41-2 4-bromo-phenol 
• 156755-23-6 6-bromo-4-phenyl-3,4-dihydro-2H-chromen-2-one 
• 156755-24-7 methyl 3-[2-(benzyloxy)-5-bromophenyl]-3-phenylpropanoate 
• 250214-37-0 (+/-)-toluene-4-sulphonic acid 3-(2-benzyloxy-5-bromophenyl)-3-phenylpropyl ester 
• 1135493-18-3 C₂₀H₁₈O₈*C₂₈H₃₄BrNO 
• 701906-29-8 (+)-N,N-Diisopropyl-3-(2-benzyloxy-5-carboxyphenyl)-3-phenylpropylamine 
• 754159-68-7 4-(benzyloxy)-3-[(1R)-3-(dipropan-2-ylamino)-1-phenylpropyl]benzoic acid 
• 1350477-43-8 (-)-N,N-diisopropyl-3-(2-benzyloxy-5-carboxyphenyl)-3-phenylpropylamine (-)-di-p-toluoyl-L-tartaric acid 
• 760147-33-9 (+)-N,N-diisopropyl-3-(2-benzyloxy-5-carboxyphenyl)-3-phenylpropylamine 

Downstream Products

• 156755-37-2 {4-(benzyloxy)-3-[(1R)-3-(dipropan-2-ylamino)-1-phenylpropyl]phenyl}methanol 
• 848768-06-9 (R)-3-[2-(benzyloxy)-5-methylphenyl]-N,N-diisopropyl-3-phenylpropan-1-amine 
• 207679-81-0 (R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)-phenol 
• 286930-02-7 fesoterodine 
• 286930-03-8 fesoterodine fumarate 
• 286930-03-8 fesoterodine fumarate 
• 214601-12-4 (R)-N,N-diisopropyl-3-phenyl-3-(5-formyl-2-hydroxyphenyl)propyl-1-amine 
• 214601-16-8 (R)-(-)-3-(3-diisopropylamino-1-phenylpropyl)-4-hydroxybenzoic acid methyl ester 
• 250214-44-9 2-(3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxyl-methyl)phenyl isobutyrate 
• 1076199-77-3 racemic 3-(3-N,N'-diisopropylamino-1-phenyl-propyl)-4-hydroxy-benzoic acid 
• 156755-20-3 PNU 200577 l-mandelate salt 
• 1390644-34-4 isobutyric acid 2-((R)-3-diisopropylammonium-1-phenyIpropyl)-4-(hydroxymethyl)phenyl ester (R)-acetoxy(phenyl)acetate 
• 1390644-38-8 (R)-2-(3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxylmethyl)phenylmethacrylate mandelate 
• 1390644-37-7 (R)-2-(3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxylmethyl)phenyl methacrylate 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF FESOTERODINE OR ITS SALTS

The present invention relates to a process for the preparation of fesoterodine or its salts.

PROCESSES FOR THE PREPARATION OF FESOTERODINE

The invention relates to improved process for the preparation of fesoterodine and its pharmaceutically acceptable salt, specifically fesoterodine fumarate of formula (1). The invention relates to solid state forms of a novel salt of fesoterodine and process for the preparation thereof. The invention also relates to highly pure fesoterodine fumarate substantially free of impurity X at RRT 1.37. The invention also provides solid particles of pure fesoterodine fumarate wherein 90 volume-percent of the particles (D90) have a size of higher than 200 microns.

IMPROVED PROCESS FOR DIPHENYLPROPYLAMINE DERIVATIVES

The present invention relates to an improved process for the preparation of biologically active diphenylpropylamine derivatives. The present invention specifically relates to an improved fesoterodine of formula (I) and its pharmaceutically acceptable salts.