cas 183305-24-0, N-[2-[5-(Aminoiminomethyl)-2-hydroxyphenoxy]-6-[3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]-3,5-difluoro-4-pyridinyl]-N-methylglycine

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183305-24-0

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Discovery of N-[2-[5-[amino(imino)methyl]-2-hydroxyphenoxy]-3,5- difluoro-6-[3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy] pyridin-4-yl]- n-methylglycine (ZK-807834): A potent, selective, and orally active inhibitor of the blood coagulation enzyme fac
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Phillips,Buckman,Davey,Eagen,Guilford,Hinchman,Ho,Koovakkat,Liang,Light,Mohan,Ng,Post,Shaw,Smith,Subramanyam,Sullivan,Trinh,Vergona,Walters,White,Whitlow,Wu,Xu,Morrissey
p. 3557 - 3562
(2007/10/03)

Benzamidine derivatives and their use as anti-coagulants
This invention is directed to benzamidine derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.
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(2008/06/13)

Chemical Properties

Boiling Point: 635.4 °C at 760 mmHg
Flash Point:338.1 °C
Density: 1.51 g/cm³
Vapor Pressure: 5.15E-17mmHg at 25°C
Refractive Index: 1.664
PKA: 3.25±0.10(Predicted)
PSA: 156.60000
LogP: 2.66960

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183305-24-0

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Chemical Properties

Boiling Point: 635.4 °C at 760 mmHg

Flash Point:338.1 °C

Density: 1.51 g/cm³

Vapor Pressure: 5.15E-17mmHg at 25°C

Refractive Index: 1.664

PKA: 3.25±0.10(Predicted)

PSA: 156.60000

LogP: 2.66960

Global suppliers and manufacturers of 183305-24-0total 9 suppliers on LookChem

Article Database

183305-24-0

Articles about 183305-24-0Total 2 be found

More Articles about upstream products of 183305-24-0

Chemical Properties

Boiling Point: 635.4 °C at 760 mmHg

Flash Point:338.1 °C

Density: 1.51 g/cm3

Vapor Pressure: 5.15E-17mmHg at 25°C

Refractive Index: 1.664

PKA: 3.25±0.10(Predicted)

PSA: 156.60000

LogP: 2.66960

Global suppliers and manufacturers of 183305-24-0total 9 suppliers on LookChem

Density: 1.51 g/cm³