Synthesis and Biological Evaluation of Novel Dispiro Compounds based on 5-Arylidenehydantoins and Isatins as Inhibitors of p53–MDM2 Protein–Protein Interaction
[Figure not available: see fulltext.] A series of novel hydantoin-based dispiroindolinones as potential small-molecule inhibitors of p53–MDM2 protein–protein interaction were synthesized by two methods, using 2-arylidenehydantoins as starting materials. S
Studies on 5-Arylidene-3-phenyl-2-methylmercaptohydantoins
The action of ammonium acetate on 5-arylidene-3-phenyl-2-methylmercaptohydantoins 1g,h in acetic acid led to the formation of the 5-arylidene-3-phenylhydantoin derivatives 4a,b.In absence of a solvent, ring opening and rearrangement took place with the fo
Kadry, Azza M.,Mansour, Salwa A.
p. 155 - 157
(2007/10/02)
Antihistamine in gynecology.
-
FINKBEINER
p. 438 - 441
(2007/10/07)
More Articles about upstream products of 2221-17-2