- ABSORBENT COMPOSITIONS INCLUDING AMINO-SILOXANES
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An absorbent composition including an amino-siloxane is presented. The amino- siloxane includes structure (I): wherein R1 is independently at each occurrence a C1-C6 aliphatic or aromatic radical; R2 is independ
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Paragraph 0064
(2018/11/10)
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- METHOD OF TREATING CANCER WITH A COMBINATION OF BENZYLIDENEGUANIDINE DERIVATIVES AND CHEMOTHERAPEUTIC AGENT.
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The present invention relates to a composition for use in treating a glioma or ameliorating the effects of a glioma, particularly glioblastoma, wherein said composition comprises a first active agent selected from the group consisting of a compound of for
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Page/Page column 60-61
(2017/03/08)
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- Difluoro- and trifluoro diazoalkanes-complementary approaches in batch and flow and their application in cycloaddition reactions
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Herein we report on applications of fluorinated diazoalkanes in cycloaddition reactions, with the emphasis on studying subtle differences between diverse fluorinated diazo compounds. These differences led to two major synthetic protocols in batch and flow that allow the safe and scalable synthesis of fluoroalkyl-, sulfone-substituted pyrazolines.
- Hock, Katharina J.,Mertens, Lucas,Metze, Friederike K.,Schmittmann, Clemens,Koenigs, Rene M.
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supporting information
p. 905 - 909
(2017/08/14)
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- O-ALKYL-BENZYLIDENEGUANIDINE DERIVATIVES AND THERAPEUTIC USE FOR THE TREATMENT OF DISORDERS ASSOCIATED AN ACCUMULATION OF MISFOLDED PROTEINS
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The present invention relates to a compound of formula (I), or a tautomer and/or a pharmaceutically acceptable salt thereof Formula (I), and its uses to treat a disorder associated with protein misfolding stress and in particular with an accumulation of m
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Page/Page column 74
(2016/01/25)
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- Reaction Products and Process of 2-Chloroethyl Ethyl Sulfide in Microemulsion Media
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The reaction of 2-chloroethyl ethyl sulfide was investigated in several oil-in-water microemulsions. The reaction products were identified by GC/MS, NMR, and LC/MS, and the reaction process was monitored by measuring peak height of reaction products and 2-chloroethyl ethyl sulfide with time by 1H NMR spectroscopy. The result showed that 2-chloroethyl ethyl sulfide degraded to 2-hydroxyethyl ethyl sulfide, cyclic sulfonium ion, open chain sulfonium chloro ion and sulfonium hydroxyl ion, and the reaction proceeded via a cyclic sulfonium ion intermediate. Based on the NMR results, a pseudoternary model was established for the reaction process of 2-chloroethyl ethyl sulfide in microemulsion.
- Mei-Ling, Lei,Hai-Ling, Xi,Ming, Shen,Ling, Yuan,Shi-Tong, Han
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p. 387 - 393
(2014/03/21)
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- Synthesis, characterization, and heterobimetallic cooperation in a titanium-chromium catalyst for highly branched polyethylenes
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A heterobimetallic catalyst, {Ti - Cr}, consisting of a constrained-geometry titanium olefin polymerization center (CGCEtTi) covalently linked to a chromium bis(thioether)amine ethylene trimerization center (SNSCr) was synthesized and fully characterized. In ethylene homopolymerizations it affords linear low-density polyethylene with molecular weights as high as 460 kg·mol-1 and exclusively n-butyl branches in conversion-insensitive densities of ~18 branches/1000 carbon atoms, which are ~17 and ~3 times (conversion-dependent), respectively, those achieved by tandem mononuclear CGCEtTi and SNSCr catalysts under identical reaction conditions.
- Liu, Shaofeng,Motta, Alessandro,Delferro, Massimiliano,Marks, Tobin J.
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supporting information
p. 8830 - 8833
(2013/07/26)
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