- · Trichoderma [...] (Trichodermareesei) 8H (FERMP-20174) strain, and crystalline cellulose production of high activity of hydrolysis transglycosylation
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PROBLEM TO BE SOLVED: To provide a new microorganism having high hydrolytic activity to a crystalline cellulose, a method for producing the microorganism and a method for producing a cellulase having high hydrolytic activity to crystalline cellulose by using the microorganism. ?SOLUTION: The invention relates to Trichoderma reesei having high hydrolytic activity to crystalline cellulose, a method for producing the Trichoderma reesei by preparing a dry green-colored mature conidium from a mold having cellulose decomposing activity, preparing a swollen conidium from the dry conidium, preparing a swollen conidium having a higher order autoploidic nucleus from the swollen conidium, preparing a swollen conidium having a plurality of genetic recombinant nuclei from the above conidium and selecting a microorganism having high hydrolytic activity to crystalline cellulose from the recombinant conidium by using a selection substrate, and a method for producing the cellulase having high hydrolytic activity to crystalline cellulose comprising the culture of Trichoderma reesei, the filtration of the culture liquid and the collection of the cellulase from the filtrate. ?COPYRIGHT: (C)2006,JPOandNCIPI ?
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- Imine derivatives as new potent and selective CB2 cannabinoid receptor agonists with an analgesic action
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In this study, a novel series of CB2 receptor agonist imine derivatives, 1-6, was synthesized and evaluated for activity against the CB2 receptor. In a previous paper we reported the synthesis and SARs of thiazole derivative 1, a pot
- Ohta, Hiroshi,Ishizaka, Tomoko,Tatsuzuki, Makoto,Yoshinaga, Mitsukane,Iida, Izumi,Yamaguchi, Tomomi,Tomishima, Yasumitsu,Futaki, Nobuko,Toda, Yoshihisa,Saito, Shuji
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p. 1111 - 1124
(2008/09/17)
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- IMINE COMPOUND
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An imine compound represented by the formula: wherein A represents a heterocyclic group; R1, R2, an R3 each represent a hydrogen atom, a halogen atom, a C1-10 alkyl group optionally substituted with an aryl grou
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Page/Page column 36-37
(2008/06/13)
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- Adamantyl-pyrazole carboxamides as inhibitors of 11B-hydroxysteroid dehydrogenase
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Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
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Page/Page column 63
(2008/06/13)
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