- A CONNVENIENT METHOD FOR THE LARGE SCALE PREPARATION OF (E)-4-OXO-2-BUTENOIC ACID ETHYL ESTER
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A one step synthesis of (E)-4-oxo-2-butenoic acid ethyl ester via the reaction of ethyl 2-ethoxy-2-hydroxyacetate and (formylmethylene)triphenylphosphorane is described.The method proceeds in good yeild on a molar scale.
- Franz, Robert G.,Weinstock, Joseph
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p. 1913 - 1918
(2007/10/02)
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- SYNTHESE STEREOSELECTIVE DU DECADIENE-2(E), 4(Z)OATE D'ETHYLE. A PARTIR D'UN MONOACETAL DU GLYOXAL
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The glyoxal monoacetal 2, now readily available in bulk quantity, is a very useful synthon for the dienes-1,3 synthesis, as illustrated in the stereoselective preparation of ethyl 2E,4Z-decadienoate using two Wittig-type olefination reactions.
- Stambouli, A.,Amouroux, R.,Chastrette, M.
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p. 5301 - 5302
(2007/10/02)
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- DISSYMETRATION DE LA MOLECULE DU GLYOXAL 1-SYNTHESE ET REACTIVITE DE L'ACETOXY-1 TRIETHOXY-1,2,2 ETHANE
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Acetoxy-1 triethoxy-1,2,2 ethane, a dissymetric derivative of glyoxal, is prepared and reacted with various bases and nucleophiles, as amines, cyanotrimethylsilane, organometallic and WITTIG reagents.Various acetals are obtained, leading to α-fonctionalized aldehydes.
- Stambouli, A.,Chastrette, F.,Amouroux, R.,Chastrette, M.,Mattioda, G.,Blanc, A.
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p. 4149 - 4152
(2007/10/02)
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