- A radical cyclization cascade of 2-alkynylbenzonitriles with sodium arylsulfinates
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A convenient radical cyclization cascade procedure for the construction of sulfonated indenones from 2-alkynylbenzonitriles and sodium arylsulfinates has been explored under mild reaction conditions. The present methodology offers a low-cost and operationally straightforward approach to synthesizing various sulfonated indenones in moderate to good yields by simple use of cheap sodium persulfate as an oxidant and environmentally benign water as a co-solvent.
- Zhou, Bang,Chen, Wenqi,Yang, Yuzhong,Yang, Yuan,Deng, Guobo,Liang, Yun
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p. 7959 - 7963
(2018/11/21)
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- SUBSTITUTED QUINOLONES III
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The invention relates to substituted quinolones and to methods for their preparation as well as to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
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Page/Page column 9-10
(2009/07/25)
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- Synthesis of C-linked immobilized analogs of aloisine A by 'click' chemistry
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An efficient approach for the immobilization of a series of analogs of aloisine A, an in vitro inhibitor of protein kinases, to polymeric supports via a [3+2] cycloaddition reaction is reported.
- Haddoub, Rose,Gueyrard, David,Goekjian, Peter G.
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body text
p. 741 - 744
(2009/04/19)
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- Substituted quinolones II
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The invention relates to substituted quinolones of formula (I) and to methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, in particu
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Page/Page column 9
(2008/12/04)
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- SUBSTITUTED QUINOLONES
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The invention relates to substituted quinolones methods for production and use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases, in particular, for use as antiviral agents, in particular, against cytomegaloviruses.
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Page/Page column 47-48
(2010/02/15)
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- Simplified Synthesis of the Precursor for the Azo Dye Chlorindazone DS
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Recently, Chlorindazone DS 1 has become an important analytical reagent for the detection of gunshot residues from newly introduced ammunition. A simplified synthesis of the precursor of the azo dye 1, 3-amino-6-chloroindazole (2), from commercially available 2,4-dichlorobenzonitrile (3a) has been described. The physical and spectroscopical properties of the known compounds 1 and 2 have been completed. 2-Chloro-4-hydrazinobenzonitrile (4a), 2-bromo-4-hydrazinobenzonitrile (4b) and a new azo dye, 1-(3′-chloro-4′-cyanobenzene-1′-ylazo)-2-hydroxynaphthalene-3, 6-disulfonic acid, disodium salt (5), have been investigated.
- Voss,Eichner
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p. 201 - 204
(2007/10/03)
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