57381-49-4

Basic information

• Product Name: 2-BROMO-4-CHLOROBENZONITRILE
• Synonyms: 2-BROMO-4-CHLOROBENZONITRILE;2-bromo-4-chlorophenyl-carbonitrile
• CAS NO: 57381-49-4
• Molecular Formula: C₇H₃BrClN
• Molecular Weight: 216.46242
• Mol File: 57381-49-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 284.0±25.0℃ (760 Torr)
• Flash Point: 125.6±23.2℃
• Appearance: /
• Density: 1.74±0.1 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.003mmHg at 25°C
• Refractive Index: 1.623
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-BROMO-4-CHLOROBENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-4-CHLOROBENZONITRILE(57381-49-4)
• EPA Substance Registry System: 2-BROMO-4-CHLOROBENZONITRILE(57381-49-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 57381-49-4(Hazardous Substances Data)

Usage

Chemical Properties

off-white crytalline

InChI:InChI=1/C7H3BrClN/c8-7-3-6(9)2-1-5(7)4-10/h1-3H

Upstream product

• 936-08-3 2-bromo-4-chlorobenzoic acid 
• 1379427-96-9 1-(2-bromo-4-chlorophenyl)-N-hydroxymethanimine 
• 84459-33-6 2-bromo-4-chlorobenzaldehyde 
• 623-03-0 4-Cyanochlorobenzene 
• 131002-01-2 2-bromo-4-chlorobenzamide 

Downstream Products

• 16889-21-7 3-amino-6-chloro-1H-indazole 
• 263845-82-5 2-bromo-4-hydrazinylbenzonitrile 
• 131002-01-2 2-bromo-4-chlorobenzamide 
• 934180-42-4 2-(benzylthio)-4-chlorobenzamide 
• 1339650-77-9 4-chloro-2-mercaptobenzonitrile 
• 84459-33-6 2-bromo-4-chlorobenzaldehyde 
• 1313762-44-5 2-vinyl-5-chlorobenzaldehyde 
• 26491-49-6 4-chloro-N-phenyl phthalimide 
• 1129540-63-1 2-bromo-4-morpholinobenzonitrile 
• 131002-09-0 6-chloroisoquinolin-1(2Η)-one 

Relevant articles and documents

A radical cyclization cascade of 2-alkynylbenzonitriles with sodium arylsulfinates

A convenient radical cyclization cascade procedure for the construction of sulfonated indenones from 2-alkynylbenzonitriles and sodium arylsulfinates has been explored under mild reaction conditions. The present methodology offers a low-cost and operationally straightforward approach to synthesizing various sulfonated indenones in moderate to good yields by simple use of cheap sodium persulfate as an oxidant and environmentally benign water as a co-solvent.

SUBSTITUTED QUINOLONES III

The invention relates to substituted quinolones and to methods for their preparation as well as to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.

SUBSTITUTED QUINOLONES

The invention relates to substituted quinolones methods for production and use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases, in particular, for use as antiviral agents, in particular, against cytomegaloviruses.