- Synthesis method of 4-alkyl biphenylacetylene
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The invention discloses a synthesis method of 4-alkyl biphenyl acetylene. The synthesis method comprises the following steps: carrying out catalytic hydrogenation reaction on 4-alkyl diketone to obtain 4-alkyl biphenyl; then reacting the 4-alkyl biphenyl with halogen to obtain 4-halogen-4 '-alkyl biphenyl; and allowing 4-halo-4 '-alkyl biphenyl and an ethynylation reagent to be subjected to a coupling reaction to obtain a compound shown in a formula (IV) under the action of alkali. The method creatively adopts a palladium catalyst and lewis acid combined catalytic system to carry out deoxidation reaction on 4-alkyl diketone, and has good selectivity and high yield; in addition, hydrogen is used as a hydrogen source, a byproduct is only water, and the method is environment-friendly.
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Paragraph 0039; 0041
(2021/06/13)
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- The Multiple Facets of Iodine(III) Compounds in an Unprecedented Catalytic Auto-amination for Chiral Amine Synthesis
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Iodine(III) reagents are used in catalytic one-pot reactions, first as both oxidants and substrates, then as cross-coupling partners, to afford chiral polyfunctionalized amines. The strategy relies on an initial catalytic auto C(sp3)?H amination of the iodine(III) oxidant, which delivers an amine-derived iodine(I) product that is subsequently used in palladium-catalyzed cross-couplings to afford a variety of useful building blocks with high yields and excellent stereoselectivities. This study demonstrates the concept of self-amination of the hypervalent iodine reagents, which increases the value of the aryl moiety.
- Buendia, Julien,Grelier, Gwendal,Darses, Benjamin,Jarvis, Amanda G.,Taran, Frédéric,Dauban, Philippe
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supporting information
p. 7530 - 7533
(2016/07/06)
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- Synthesis of large [2]rotaxanes. the relationship between the size of the blocking group and the stability of the rotaxane
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[2]Rotaxanes with large macrocyclic phenanthrolines were prepared by the template method, and the stability of the rotaxanes was examined. Compared to the tris(biphenyl)methyl group, the tris(4-cyclohexylbiphenyl)methyl group was a larger blocking group, and the rate of the dissociation of the components decreased significantly when the thermal stability of a rotaxane with a 41-memebered ring was examined. We also succeeded in the synthesis of larger rotaxanes by the oxidative dimerization of alkynes with these bulky blocking groups, utilizing the catalytic activity of the macrocyclic phenanthroline-Cu complex.
- Saito, Shinichi,Takahashi, Eiko,Wakatsuki, Kouta,Inoue, Kazuhiko,Orikasa, Tomoko,Sakai, Kenta,Yamasaki, Ryu,Mutoh, Yuichiro,Kasama, Takeshi
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p. 3553 - 3560
(2013/06/04)
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- Synthesis and preliminary testing of molecular wires and devices
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Presented here are several convergent synthetic routes to conjugated oligo(phenylene ethynylene)s. Some of these oligomers are free of functional groups, while others possess donor groups, acceptor groups, porphyrin interiors, and other heterocyclic interiors for various potential transmission and digital device applications. The syntheses of oligo(phenylene ethynylene)s with a variety of end groups for attachment to numerous metal probes and surfaces are presented. Some of the functionalized molecular systems showed linear, wire-like, current versus voltage (I(V)) responses, while others exhibited nonlinear I(V) curves for negative differential resistance (NDR) and molecular random access memory effects. Finally, the syntheses of functionalized oligomers are described that can form self-assembled monolayers on metallic electrodes that reduce the Schottky barriers. Information from the Schottky barrier studies can provide useful insight into molecular alligator clip optimizations for molecuar electronics.
- Tour, James M.,Rawlett, Adam M.,Kozaki, Masatoshi,Yao, Yuxing,Jagessar, Raymond C.,Dirk, Shawn M.,Price, David W.,Reed, Mark A.,Zhou, Chong-Wu,Chen, Jia,Wang, Wenyong,Campbell, Ian
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p. 5118 - 5134
(2007/10/03)
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