- Rapid intramolecular and C-O cleavage reactions of a phosphate triester catalysed by a neighbouring hydroxyl group
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Three consecutive reactions are observed when the phosphate triester 6 is hydrolysed. At pH 12 M. 12 is then hydrolysed by C-O cleavage to give the diester 11. In base, the first two reactions are complete almost instantaneously, and the final phosphorus-containing products are (3,4-dichlorophenoxy)methyl methyl phosphate diester, and the methyl phosphate dianion. These must come from C-O cleavage reactions of diester 14 and the rearranged benzylic triester 15, which rapidly eliminate phosphate ester leaving groups to give the same quinone methide.
- Kirby, Anthony J.,Marriott, Robert E.
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- Synthesis of Aromatic Monoterpenyl Geranyl Ethers as Possible Insect Juvenile Hormon Mimics
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Substituted phenyl geranyl (IX-XV, XXIV-XXVIII) and 7-methoxygeranyl ethers (XVI-XXIII, XXVIII) have been synthesised as possible juvenile hormon (JH) mimics.Out of these ethers only XVII, XVIII and XXIII show low JH activity.
- Phadnis, A. P.,Nanda, B.,Patwardhan, Sarita A.,Gupta, A. S.
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p. 1098 - 1102
(2007/10/02)
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- Isothymol: Synthesis and Biogenesis
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Isothymol (I), the C10-analogue of elvirol (II), has been synthesized from 2-hydroxy-5-methylacetophenone, and synthetic (I) is shown to be identical with natural isothymol.A probable biogenesis of I has been suggested.
- Dinge, A. S.,Kirtany, J. K.,Paknikar, S. K.
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p. 245 - 246
(2007/10/02)
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