78719-73-0

Basic information

• Product Name: 2-Hydroxy-α,α,5-trimethylbenzyl alcohol
• Synonyms: 2-Hydroxy-α,α,5-trimethylbenzyl alcohol
• CAS NO: 78719-73-0
• Molecular Weight: 166.22
• Mol File: 78719-73-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Hydroxy-α,α,5-trimethylbenzyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hydroxy-α,α,5-trimethylbenzyl alcohol(78719-73-0)
• EPA Substance Registry System: 2-Hydroxy-α,α,5-trimethylbenzyl alcohol(78719-73-0)

Safety Data

• Hazardous Substances Data: 78719-73-0(Hazardous Substances Data)

Upstream product

• 917-64-6 methyl magnesium iodide 
• 22717-57-3 methyl 6-hydroxy-m-toluate 
• 14002-89-2 4,6-dimethyl-chromen-2-one 
• 1450-72-2 5-methyl-2-hydroxyacetophenone 
• 74-88-4 methyl iodide 
• 6627-55-0 2-bromo-p-cresol 
• 67-64-1 acetone 

Downstream Products

• 94853-45-9 1-((E)-3,7-Dimethyl-octa-2,6-dienyloxy)-2-isopropenyl-4-methyl-benzene 
• 94853-33-5 2-[2-((E)-3,7-Dimethyl-octa-2,6-dienyloxy)-5-methyl-phenyl]-propan-2-ol 
• 174867-46-0 2-(1-hydroxy-1-methylethyl)-4-methylphenyl tert-butyldimethylsilylether 
• 64298-10-8 1-methoxy-4-methyl-2-(prop-1-en-2-yl)benzene 
• 94853-39-1 2-[2-((E)-7-Methoxy-3,7-dimethyl-oct-2-enyloxy)-5-methyl-phenyl]-propan-2-ol 
• 78719-74-1 4-Methyl-2-(2,4,4,6-tetramethyl-chroman-2-yl)-phenol 
• 174867-64-2 (3,4-dichlorophenoxy)methyl 2-(1-hydroxy-1-methylethyl)-4-methylphenyl methyl phosphate 
• 4427-56-9 Isothymol 
• 78719-75-2 2-(2-Acetoxy-5-methyl-phenyl)-2,4,4,6-tetramethyl-chroman 
• 65490-14-4 2-isopropenyl-4-methylphenol 

Relevant articles and documents

Rapid intramolecular and C-O cleavage reactions of a phosphate triester catalysed by a neighbouring hydroxyl group

Three consecutive reactions are observed when the phosphate triester 6 is hydrolysed. At pH 12 M. 12 is then hydrolysed by C-O cleavage to give the diester 11. In base, the first two reactions are complete almost instantaneously, and the final phosphorus-containing products are (3,4-dichlorophenoxy)methyl methyl phosphate diester, and the methyl phosphate dianion. These must come from C-O cleavage reactions of diester 14 and the rearranged benzylic triester 15, which rapidly eliminate phosphate ester leaving groups to give the same quinone methide.

Isothymol: Synthesis and Biogenesis

Isothymol (I), the C10-analogue of elvirol (II), has been synthesized from 2-hydroxy-5-methylacetophenone, and synthetic (I) is shown to be identical with natural isothymol.A probable biogenesis of I has been suggested.