Synthesis of functionalised azecine and azonine derivatives via an enolate assisted aza Claisen rearrangement
This paper describes the synthesis of functionalised azecine and azonine derivatives incorporating the adrenaline motif. In a key step, an enolate assisted aza Claisen rearrangement was employed to interconvert from 6- and 5-membered heterocycles to their corresponding 10- and 9-membered lactams.
Bremner, John B.,Perkins, David F.
p. 2659 - 2665
(2007/10/03)
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