Fluorous affinity purification of oligonucleotides
Nucleoside phosphoramidites bearing a fluorous dimethoxytrityl (FDMT) group were used to synthesize fluorous-tagged oligonucleotides, which were subjected to solid-phase extraction using a pH-stable fluorinated adsorbent. On-column detritylation afforded
Pearson, William H.,Berry, David A.,Stoy, Patrick,Jung, Kee-Yong,Sercel, Anthony D.