865758-45-8 Usage
Description
5'-O-FDMT-N4-BENZOYL-2'-DEOXYCYTIDINE CEP is a chemical entity that serves as a key component in the synthesis of oligodeoxyribonucleotides. It is characterized by its unique structure, which includes a 5'-O-FDMT group, an N4-benzoyl group, and a 2'-deoxycytidine moiety. 5'-O-FDMT-N4-BENZOYL-2'-DEOXYCYTIDINE CEP plays a crucial role in the development of advanced synthetic methods and purification techniques in the field of molecular biology.
Used in Synthetic Preparation:
5'-O-FDMT-N4-BENZOYL-2'-DEOXYCYTIDINE CEP is used as a reactant/reagent in the synthetic preparation of oligodeoxyribonucleotides. Its unique structure allows for the efficient synthesis of these biologically significant molecules, which are essential for various applications in molecular biology and medicine.
Used in Solid-Phase Fluorous Affinity Purification:
In the field of molecular biology, purification of synthesized molecules is a critical step. 5'-O-FDMT-N4-BENZOYL-2'-DEOXYCYTIDINE CEP is used as a reactant/reagent in solid-phase fluorous affinity purification, a technique that employs pH-stable fluorinated adsorbents. This method offers a highly selective and efficient approach to purifying oligodeoxyribonucleotides, ensuring their purity and integrity for downstream applications.
Used in Pharmaceutical Industry:
5'-O-FDMT-N4-BENZOYL-2'-DEOXYCYTIDINE CEP is used as a key intermediate in the development of pharmaceutical compounds, particularly those targeting genetic disorders and diseases. Its role in the synthesis of oligodeoxyribonucleotides makes it a valuable asset in the creation of therapeutic agents that can modulate gene expression and treat various conditions.
Used in Research and Development:
In the realm of research and development, 5'-O-FDMT-N4-BENZOYL-2'-DEOXYCYTIDINE CEP is used as a reactant/reagent for the synthesis and purification of oligodeoxyribonucleotides. Its application in this field facilitates the exploration of novel molecular mechanisms, the development of new diagnostic tools, and the advancement of therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 865758-45-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,5,7,5 and 8 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 865758-45:
(8*8)+(7*6)+(6*5)+(5*7)+(4*5)+(3*8)+(2*4)+(1*5)=228
228 % 10 = 8
So 865758-45-8 is a valid CAS Registry Number.
865758-45-8Relevant articles and documents
Fluorous affinity purification of oligonucleotides
Pearson, William H.,Berry, David A.,Stoy, Patrick,Jung, Kee-Yong,Sercel, Anthony D.
, p. 7114 - 7122 (2005)
Nucleoside phosphoramidites bearing a fluorous dimethoxytrityl (FDMT) group were used to synthesize fluorous-tagged oligonucleotides, which were subjected to solid-phase extraction using a pH-stable fluorinated adsorbent. On-column detritylation afforded
