cas 99735-43-0, (1'R, 3R)-1-(1'-PHENYLETHYL)-5-OXO-3-PYRROLIDINE CARBOXYLIC ACID | Articles data ｜lookchem

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99735-43-0

Articles about 99735-43-0Total 5 be found

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AMIDE COMPOUND
The present invention relates to compound (I) or a salt thereof which has a RORγt inhibitory action. In the formula (I), each symbol is as defined in the specification.
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Paragraph 0596

(2016/08/17)

Adamantyl Iminocarbonyl-Substituted Pyrimidines As Inhibitors Of 11-Beta-HSD1 826
A compound of formula (I): and pharmaceutically-acceptable salts thereof, wherein the variable groups are defined within; their use in the inhibition of 11βHSD1, processes for making them and pharmaceutical compositions comprising them are also described
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Page/Page column 24

(2011/05/03)

SPIRO CONDENSED PIPERIDNES AS MODULATORS OF MUSCARINIC RECEPTORS
The present invention relates to modulators of muscarnic receptors of formula (I). The present invention also provides impositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
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Page/Page column 51

(2008/06/13)

BENZOIC ACID COMPOUNDS AND USE THEREOF AS MEDICAMENTS
Benzoic acid compounds of the formula STR1 wherein each symbol is as defined in the specification, optical isomers thereof and pharmaceutically acceptable salts thereof; pharmaceutical composition comprising this compound and pharmaceutically acceptable additive; and serotonin 4 receptor agonists, gastrointestinal prokinetic agents and therapeutic agents for various gastrointestinal diseases, which comprise this compound as active ingredient. The compounds of the present invention have high and selective affinity for serotonin 4 receptor, and show agonistic effects thereon. Accordingly, they are useful medications for the prophylaxis and treatment of various gastrointestinal diseases, central nervous disorders, cardiac function disorders, urinary diseases, and the like, as well as useful anti-nociceptors for analgesic use which increase threshold of pain.
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(2008/06/13)

Enantiomers of 1-Ethyl-7--1-pyrrolidinyl>-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid: Preparation and Biological Activity
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Culbertson, Townley P.,Domagala, John M.,Nichols, Jeffery B.,Priebe, Stephen,Skeean, Richard W.
p. 1711 - 1715
(2007/10/02)

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Chemical Properties

Melting Point: 210-213oC(lit.)
Boiling Point: 460.1°Cat760mmHg
Flash Point:232.1°C
Density: 1.267g/cm³
Storage Temp.:Sealed in dry,Room Temperature
Vapor Pressure: 2.92E-09mmHg at 25°C
PKA: 4.48±0.20(Predicted)
PSA: 57.61000
LogP: 1.61860

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