99735-43-0

Basic information

• Product Name: (1'R, 3R)-1-(1'-PHENYLETHYL)-5-OXO-3-PYRROLIDINE CARBOXYLIC ACID
• Synonyms: (1'R, 3R)-1-(1'-PHENYLETHYL)-5-OXO-3-PYRROLIDINE CARBOXYLIC ACID;(1'R,3R)-(+)-1-(1'-PHENYLETHYL)-5-OXO-3-PYRROLIDINECARBOXYLIC ACID;(1R,3R)-1-(1'-PHENYLETHYL)-5-OXO-3-PYRROLIDINECARBOXYLIC ACID;(1R,3R)-1-(1-PHENYLETHYL)5-OXO-3-PYRROL;(1'R,3R)-1-(1'-Phenylethyl)-5-oxo-3-pyrrolidine carboxylic acid,98%;(3R)-5-Oxo-1-[(1R)-1-phenylethyl]pyrrolidine-3-carboxylic acid;(3S)-5-Oxo-1-(1-phenylethyl)pyrrolidine-3-carboxylic acid;(1'R,3R)-(+)-1-(1'-Phenylethyl)-5-oxo-3-pyrrolidinecarboxylic acid 97%
• CAS NO: 99735-43-0
• Molecular Formula: C₁₃H₁₅NO₃
• Molecular Weight: 233.26
• Product Categories: Chiral Building Blocks;Heterocyclic Building Blocks;Pyrrolidines
• Mol File: 99735-43-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 210-213 °C(lit.)
• Boiling Point: 460.1°Cat760mmHg
• Flash Point: 232.1°C
• Appearance: /
• Density: 1.267g/cm³
• Vapor Pressure: 2.92E-09mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.48±0.20(Predicted)
• CAS DataBase Reference: (1'R, 3R)-1-(1'-PHENYLETHYL)-5-OXO-3-PYRROLIDINE CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (1'R, 3R)-1-(1'-PHENYLETHYL)-5-OXO-3-PYRROLIDINE CARBOXYLIC ACID(99735-43-0)
• EPA Substance Registry System: (1'R, 3R)-1-(1'-PHENYLETHYL)-5-OXO-3-PYRROLIDINE CARBOXYLIC ACID(99735-43-0)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 99735-43-0(Hazardous Substances Data)

Usage

General Description

(1'R, 3R)-1-(1'-phenylethyl)-5-oxo-3-pyrrolidine carboxylic acid, also known as (-)-N-phenylisoserine, is a white crystalline powder with a molecular formula of C13H15NO3. It is a derivative of the neurotransmitter serotonin and has been studied for its potential as an antidepressant and anxiolytic. This chemical compound is also known for its ability to modulate 5-HT1A and 5-HT1B serotonin receptors, which are important targets for medications used to treat mood disorders and anxiety. Additionally, it has been investigated for its potential use in treating substance abuse disorders. However, more research is needed to fully understand its pharmacological effects and potential therapeutic applications.

InChI:InChI=1/C13H15NO3/c1-9(10-5-3-2-4-6-10)14-8-11(13(16)17)7-12(14)15/h2-6,9,11H,7-8H2,1H3,(H,16,17)/p-1/t9-,11-/m1/s1

Upstream product

• 97-65-4 2-methylenesuccinic acid 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 99735-45-2 methyl (3R)-1-<(R)-1-phenylethyl>-5-oxo-3-pyrrolidinecarboxylate 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 617-52-7 Dimethyl itakonate 
• 915302-94-2 (3RS)-1-<(R)-1-phenylethyl>-5-oxo-3-pyrrolidinecarboxylic acid 

Downstream Products

• 269407-03-6 (R)-N-methoxy-N-methyl-5-oxo-1-((R)-1-phenylethyl)pyrrolidine-3-carboxamide 
• 1292289-46-3 (4S)-4-(aminomethyl)pyrrolidin-2-one 
• 173340-22-2 (4S)-4-(aminomethyl)-1-[(1R)-1-phenylethyl]pyrrolidin-2-one 
• 1292289-47-4 (3R)-5-oxo-1-[(1R)-1-phenylethyl]pyrrolidine-3-carbonitrile 
• 173340-21-1 (3R)-5-oxo-1-[(1R)-1-phenylethyl]pyrrolidine-3-carboxamide 
• 190957-22-3 (4R,1'R)-1-(1'-phenylethyl)-4-hydroxymethylpyrrolidin-2-one 
• 252051-12-0 (4R,1'R)-[1-(1'-phenylethyl)-2-oxopyrrolidin-4-yl]carboxaldehyde 
• 146511-96-8 (R)-4-acetyl-1-((R)-1-phenylethyl)pyrrolidine-2-one 
• 1319736-51-0 (4R)-4-((S)-1-hydroxyethyl)-1-((R)-1-phenylethyl)pyrrolidine-2-one 
• 1319736-58-7 (4R)-4-((R)-1-hydroxyethyl)-1-((R)-1-phenylethyl)pyrrolidine-2-one 
• 1319736-72-5 C₂₁H₁₆Cl₄N₂O₃ 
• 1319736-76-9 C₁₆H₂₁NO₃ 
• 1319736-78-1 (4R)-4-(1-hydroxy-3-methoxypropyl)-1-((R)-1-phenylethyl)pyrrolidine-2-one 
• 1319736-81-6 (R)-4-(tert-butyl-dimethyl-silanyloxymethyl)-3,3-dimethyl-1-((R)-1-phenyl-ethyl)pyrrolidine-2-one 

Relevant articles and documents

AMIDE COMPOUND

The present invention relates to compound (I) or a salt thereof which has a RORγt inhibitory action. In the formula (I), each symbol is as defined in the specification.

SPIRO CONDENSED PIPERIDNES AS MODULATORS OF MUSCARINIC RECEPTORS

The present invention relates to modulators of muscarnic receptors of formula (I). The present invention also provides impositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

Enantiomers of 1-Ethyl-7--1-pyrrolidinyl>-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid: Preparation and Biological Activity

-