102732-63-8

Basic information

• Product Name: 2-(1H-pyrazol-5-yl)acetic acid
• Synonyms: 2-(1H-pyrazol-5-yl)acetic acid;(1H-Pyrazol-3-yl)-acetic acid;2-(1H-pyrazol-3-yl)acetic acid hydrochloride;2-(1H-Pyrazol-3-yl)acetic acid;1H-pyrazole-3-acetic acid;3-Pyrazolylacetic acid;2-(1H-Pyrazol-3-yl);(1H-Pyrazol-3-Yl)-Acetic Acid(WX613221)
• CAS NO: 102732-63-8
• Molecular Formula: C5H6N2O2
• Molecular Weight: 126.11334
• Mol File: 102732-63-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 387.3±17.0 °C(Predicted)
• Appearance: /
• Density: 1.426±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• PKA: 4.06±0.10(Predicted)
• CAS DataBase Reference: 2-(1H-pyrazol-5-yl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1H-pyrazol-5-yl)acetic acid(102732-63-8)
• EPA Substance Registry System: 2-(1H-pyrazol-5-yl)acetic acid(102732-63-8)

Safety Data

• Hazardous Substances Data: 102732-63-8(Hazardous Substances Data)

Usage

Uses

2-(1H-Pyrazol-5-yl)acetic Acid is used in preparation of inhibitors of cGAS.

Upstream product

• 5418-51-9 5-nitro-2-pyridone 
• 144677-14-5 2-(1H-pyrazol-3-yl)acetohydrazide 
• 5418-51-9 5-nitro-2-hydroxypyridine 
• 878678-79-6 (1H-pyrazol-3-yl)acetic acid methyl ester 
• 5118-06-9 methyl 3-hydroxy-2-thiophenecarboxylate 
• 135237-01-3 2-(1H-pyrazol-3-yl)acetonitrile 

Downstream Products

• 1071814-44-2 2-(1-methyl-1H-pyrazol-5-yl)acetic acid 
• 1177318-00-1 2-(1-methyl-1H-pyrazol-3-yl)acetic acid 
• 82668-50-6 ethyl 2-(1H-pyrazol-3-yl)acetate 

Relevant articles and documents

CONVERSION OF 5-NITRO-PYRIDONE-2 TO A PYRAZOLE DERIVATIVE

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HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS

The invention relates to a compound of formula (I) and a racemate, an enantiomer, a diastereoisomer, a geometric isomer or a pharmaceutically acceptable salt thereof, and its use as antibacterial agent.

PYRAZOLE AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS

Pyrazole compounds that are modulators of LRRK2, methods of making the compounds, and methods for using the compounds for treatment of diseases associated with LRRK2 receptor, such as Parkinson's disease.