1193-71-1

Basic information

• Product Name: 3-Amino-4,6-dimethylpyridine
• Synonyms: 5-AMINO-2,4-DIMETHYLPYRIDINE;3-AMINO-4,6-DIMETHYLPYRIDINE;IFLAB-BB F1957-0017;3-Amino-4,6-dimethylpyridine 97%;4,6-dimethyl-3-pyridinamine;3-Amino-4,6-dimethylpyridine ,98%;5-Methyl-1H-pyrrole-3-carboxylic acid ethyl ester;3-PyridinaMine, 4,6-diMethyl-
• CAS NO: 1193-71-1
• Molecular Formula: C₇H₁₀N₂
• Molecular Weight: 122.17
• Product Categories: Heterocycles;Heterocyclic Compound;Pyridine series;Amines;Pyridines
• Mol File: 1193-71-1.mol
• Article Data: 5

Chemical Properties

• Melting Point: 68 °C
• Boiling Point: 257.11 °C at 760 mmHg
• Flash Point: 133.051 °C
• Appearance: /
• Density: 1.04 g/cm³
• Vapor Pressure: 0.0148mmHg at 25°C
• Refractive Index: 1.564
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 7.54±0.18(Predicted)
• CAS DataBase Reference: 3-Amino-4,6-dimethylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-4,6-dimethylpyridine(1193-71-1)
• EPA Substance Registry System: 3-Amino-4,6-dimethylpyridine(1193-71-1)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 1193-71-1(Hazardous Substances Data)

Usage

Description

3-Amino-4,6-dimethylpyridine, also known as 3-Amino-4,6-lutidine, is a heterocyclic aromatic amine with the molecular formula C7H10N2. It features a pyridine ring substituted with an amino group at the 3 position and methyl groups at the 4 and 6 positions, making it a versatile chemical compound.

Uses

Used in Pharmaceutical Synthesis:
3-Amino-4,6-dimethylpyridine is used as a building block for the synthesis of pharmaceuticals, contributing to the development of new drugs due to its unique chemical structure and reactivity.
Used in Agrochemical Production:
In the agrochemical industry, 3-Amino-4,6-dimethylpyridine serves as a key component in the creation of various agrochemicals, enhancing crop protection and yield.
Used in Dye Manufacturing:
3-Amino-4,6-dimethylpyridine is utilized as a building block in the synthesis of dyes, providing a range of color options for different applications.
Used as a Ligand in Coordination Chemistry:
3-Amino-4,6-dimethylpyridine functions as a ligand in coordination chemistry, playing a crucial role in the formation and stabilization of metal complexes.
Used as a Catalyst in Organic Reactions:
3-Amino-4,6-dimethylpyridine acts as a catalyst to facilitate and enhance the rate of various organic reactions, improving the efficiency of chemical processes.
Used in Organic Electronics:
3-Amino-4,6-dimethylpyridine has been investigated for its potential applications in the field of organic electronics, where it may contribute to the development of new electronic materials and devices.
Used as a Corrosion Inhibitor for Metals:
In the metal industry, 3-Amino-4,6-dimethylpyridine is explored as a corrosion inhibitor, helping to protect metals from degradation and extending their service life.
It is important to handle 3-Amino-4,6-dimethylpyridine with care due to its potential health and environmental hazards, ensuring safe practices in its application and disposal.

InChI:InChI=1/C7H10N2/c1-5-3-6(2)9-4-7(5)8/h3-4H,8H2,1-2H3

Upstream product

• 23056-33-9 2-chloro-4-methyl-5-nitro-pyridine 
• 1074-99-3 2,4-dimethyl-5-nitropyridine 
• 1074-76-6 2,4-dimethyl-3-nitropyridine 
• 108-47-4 2,4-lutidine 

Downstream Products

• 213685-57-5 2-amino-3-hydroxy-4,6-dimethylpyridine 
• 1346123-74-7 1-(4,6-dimethylpyridin-3-yl)-4-(toluene-4-sulfonyl)piperazine 
• 1417332-51-4 1-(4-Methoxy-phenyl)-3,6-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (4,6-dimethyl-pyridin-3-yl)-amide 
• 76006-01-4 1-acetyl-5-methyl-1H-pyrazolo<3,4-c>pyridine 
• 76006-06-9 5-methyl-1H-pyrazolo[3,4-c]pyridine 
• 104830-09-3 2-bromo-3-iodo-4,6-dimethylpyridine 
• 97308-41-3 4,6-dimethyl-3-phenylethynyl-2-pyridinecarboxamide 
• 97308-42-4 2,4-dimethyl-6-phenyl-1,7-naphthyridin-8(7H)-one 
• 97308-40-2 4,6-dimethyl-3-phenylethynyl-2-pyridinecarbonitrile 
• 97308-39-9 3-bromo-4,6-dimethyl-2-pyridinecarbonitrile 
• 143509-34-6 2,4-dimethyl-5-hydroxypyridine N-oxide 
• 27296-77-1 2,4-dimethyl-5-hydroxypyridine 
• 860410-54-4 5-methyl-3H-pyrazolo[3,4-c]pyridine 
• 104829-98-3 3-amino-2-bromo-4,6-dimethylpyridine 

Relevant articles and documents

FACTOR XI ACTIVATION INHIBITORS

The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XI activation inhibitors.

Thrombin inhibitors

Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions having the following structure: or a pharmaceutically acceptable salt thereof, wherein b is NY or O; c is CY2or N; d is CY3or N; e is CY4or N; f is CY5or N; g is CY6or N; Y4, Y5, and Y6are independently hydrogen, C1-4alkyl, or halogen; Y1and Y2are independently hydrogen, C1-4alkyl, C3-7cycloalkyl, halogen, NH2, OH or C1-4alkoxy, and Y3is hydrogen, C1-4alkyl, C3-7cycloalkyl, halogen, —CN, NH2, OH or C1-4alkoxy; A is and W, W1, R1, R3, R4, R5, X and Z are defined in the specification.

Synthesis and Antitumor Activity of 3- and 5-Hydroxy-4-methylpyridibe-2-carboxaldehyde Thiosemicarbazones

To develop an α-(N)-heterocyclic carboxaldehyde thiosemicarbazone with clinical utility as an anticancer agent, two analogues, 3-hydroxy-4-methylpyridine-2-carboxaldehyde thiosemicarbazone (3-HMP) and 5-hydroxy-4-methylpyridine-2-carboxaldehyde thiosemicarbazone (5-HMP), of 5-hydroxypyridine-2-carboxaldehyde thiosemicarbazone (5-HP) have been designed and synthesized by two different methods. 3-HMP and 5-HMP both showed better antitumor activity than their respective parent compounds, 3-hydroxypyridine-2-carboxaldehyde thiosemicarbazone and 5-HP, in mice bearing the L1210 leukemia.