314298-13-0

Basic information

• Product Name: Benzene,1-fluoro-5-methoxy-2-methyl-4-nitro-
• Synonyms: 1-Fluoro-2-methyl-5-(methyloxy)-4-nitrobenzene;5-Fluoro-4-methyl-2-nitrophenyl methyl ether
• CAS NO: 314298-13-0
• Molecular Formula: C₈H₈FNO₃
• Molecular Weight: 185.1524232
• Product Categories: METHOXY
• Mol File: 314298-13-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 272.6±35.0 °C(Predicted)
• Appearance: /
• Density: 1.270±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Benzene,1-fluoro-5-methoxy-2-methyl-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene,1-fluoro-5-methoxy-2-methyl-4-nitro-(314298-13-0)
• EPA Substance Registry System: Benzene,1-fluoro-5-methoxy-2-methyl-4-nitro-(314298-13-0)

Safety Data

• Hazardous Substances Data: 314298-13-0(Hazardous Substances Data)

Usage

General Description

Benzene, 1-fluoro-5-methoxy-2-methyl-4-nitro- is a chemical compound with the molecular formula C?H?FNO?. It is a nitrofluoro-methoxy derivative of benzene with a methyl group attached to the 2-position. Benzene,1-fluoro-5-methoxy-2-methyl-4-nitro- is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. It is also known for its potential use as a pesticide, although its use has become more restricted due to environmental and health concerns. Benzene, 1-fluoro-5-methoxy-2-methyl-4-nitro- is considered to be a hazardous chemical and should be handled with caution.

Upstream product

• 106579-00-4 5-methoxy-2-methyl-4-nitroaniline 
• 452-78-8 3-fluoro-4-methyl phenol 
• 83341-28-0 5-fluoro-4-methyl-2-nitrophenol 
• 74-88-4 methyl iodide 

Downstream Products

• 1116230-14-8 1-isopropyl-4-(5-methoxy-2-methyl-4-nitrophenyl)piperazine 
• 1116230-00-2 tert-butyl 4-(5-methoxy-2-methyl-4-nitrophenyl) piperazine-1-carboxylate 
• 1356963-00-2 1-(5-methoxy-2-methyl-4-nitrophenyl)piperidin-4-one 
• 1356962-99-6 (R)-4-(3-fluoropyrrolidin-1-yl)-1-(5-methoxy-2-methyl-4-nitrophenyl)piperidine 
• 1356962-90-7 1-(1-(5-methoxy-2-methyl-4-nitrophenyl)piperidin-4-yl)-4-methylpiperazine 
• 1356963-01-3 2-methoxy-5-methyl-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline 
• 1356962-93-0 8-(5-Methoxy-2-methyl-4-nitrophenyl)-1,4-dioxa-8-azaspiro[4.5]decane 
• 1089281-65-1 1-[2-methyl-5-(methyloxy)-4-nitrophenyl]-4-[2-(methylsulfonyl)ethyl]piperazine 
• 1089280-88-5 Phenylmethyl 4-{1-[2-methyl-5-(methyloxy)-4-nitrophenyl]-4-piperidinyl}-1-piperazinecarboxylate 
• 314298-21-0 [2-(4-bromo-2-fluorobenzylthiocarbamoyl)-5-fluoro-4-methyl-phenoxy]-acetic acid ethyl ester 
• 314298-17-4 4-fluoro-2-methoxy-5-methyl-benzoic acid 

Relevant articles and documents

Novel(1,2,4)triazolo(1,5-a)pyridylphosphine oxide and use thereof

The present invention relates to novel(1,2,4)triazolo(1,5-a)pyridinyl phosphorus oxides and uses thereof. Wherein the compound is a compound represented by a formula I, or a pharmaceutically acceptable salt thereof, or a hydrate thereof, or a solvate thereof, or a metabolite thereof, or a stereoisomer thereof, or a tautomer thereof, or a prodrug thereof, and R1 to R5 are as defined in the specification. The compound disclosed by the invention can be used for preparing a medicine for treating and/or preventing cancers.

CHEMICAL COMPOUNDS

The present invention relates to compounds of Formula (I) and/or Formula (Ia): and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit ALK kinase activity, and thus may be used for the tr

2- [ (2-{PHENYLAMINO}-1H-PYRROLO [2, 3-D] PYRIMIDIN-4-YL) AMINO] BENZAMIDE DERIVATIVES AS IGF-1R INHIBITORS FOR THE TREATMENT OF CANCER

Novel pyrrolopyrimidines as shown in formula (I) and pharmaceutically acceptable derivatives thereof. The compounds are useful in the inhibition of IGF-1R.