68697-61-0

Basic information

• Product Name: DL-TYROSINE METHYL ESTER HCL
• Synonyms: methyl DL-tyrosinate hydrochloride;(±)-Tyrosine methyl ester hydrochloride;H-DL-Tyr-OMe;2-Amino-3-(4-hydroxyphenyl)propionic acid methyl ester hydrochloride;Methyl 2-amino-3-(4-hydroxyphenyl);DL-TYROSINE METHYL ESTER HCL
• CAS NO: 68697-61-0
• Molecular Formula: C₁₀H₁₄NO₃*Cl
• Molecular Weight: 231.67606
• EINECS: 272-084-9
• Mol File: 68697-61-0.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 330oC at 760 mmHg
• Flash Point: 153.4oC
• Appearance: /
• Vapor Pressure: 8.89E-05mmHg at 25°C
• Storage Temp.: −20°C
• CAS DataBase Reference: DL-TYROSINE METHYL ESTER HCL(CAS DataBase Reference)
• NIST Chemistry Reference: DL-TYROSINE METHYL ESTER HCL(68697-61-0)
• EPA Substance Registry System: DL-TYROSINE METHYL ESTER HCL(68697-61-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 68697-61-0(Hazardous Substances Data)

Usage

General Description

DL-Tyrosine Methyl Ester HCl is a chemical compound often used in scientific research. It's a derivative of Tyrosine, an amino acid that's critical for human health and plays a vital role in protein synthesis. The methyl ester group increases the compound's lipophilicity, enhancing its ability to cross biological membranes. The HCl denotes that it is in a hydrochloride form, enhancing its stability and solubility. DL-TYROSINE METHYL ESTER HCL is typically used in biochemical research, including studies on enzymology, neurotransmitter regulation, and pharmacological investigations.

InChI:InChI=1/C10H13NO3.ClH/c1-14-10(13)9(11)6-7-2-4-8(12)5-3-7;/h2-5,9,12H,6,11H2,1H3;1H/t9-;/m0./s1

Upstream product

• 67-56-1 methanol 
• 556-02-5 ?Tyr 
• 142847-18-5 N-(tert-butoxycarbonyl)tyrosine 

Downstream Products

• 3978-80-1 Boc-Tyr-OH 
• 70642-86-3 N-(tert-butoxycarbonyl)-D-tyrosine 
• 188576-13-8 methyl 2-[(t-butoxycarbonyl)amino]-3-(4-hydroxyphenyl)propanoate 
• 1172-65-2 2-(2-tert-Butoxycarbonylamino-3-hydroxy-propionylamino)-3-(4-hydroxy-phenyl)-propionic acid methyl ester 
• 77714-34-2 3-(4-Hydroxy-phenyl)-2-((Z)-3-oxo-propenylamino)-propionic acid methyl ester 
• 77714-34-2 3-(4-Hydroxy-phenyl)-2-((E)-3-oxo-propenylamino)-propionic acid methyl ester 
• 79397-31-2 2-[2-(4-Chloro-phenoxy)-acetylamino]-3-(4-hydroxy-phenyl)-propionic acid methyl ester 
• 97654-03-0 Mal-Pab-Tyr-OMe 
• 101469-25-4 tyrosinamide 
• 69955-04-0 2-benzylideneamino-3-(4-hydroxyphenyl)-propionic acid methyl ester 
• 137957-18-7 2-(5,5-Dimethyl-3-oxo-cyclohex-1-enylamino)-3-(4-hydroxy-phenyl)-propionic acid methyl ester 
• 556-02-5 tyrosine 
• 3410-66-0 D-tyrosine methyl ester 
• 60-18-4 L-tyrosine 

Relevant articles and documents

(2S, 3R)-3-amino-2-hydroxy-4-phenylbutyrylamide derivative as well as preparation method and application thereof

The invention discloses a (2S, 3R)-3-amino-2-hydroxy-4-phenylbutyrylamide derivative shown as a formula (I) or an optical isomer, a diastereomer and racemate mixture and pharmaceutically acceptable salt thereof as well as a preparation method and application of the (2S, 3R)-3-amino-2-hydroxy-4-phenylbutyrylamide derivative. It is shown by comparison of results of a positive control group and a model group on lymphedema prevention experiments that the compound disclosed in the invention shows obvious anti-edema activity.

NovelN-transfer reagent for converting α-amino acid derivatives to α-diazo compounds

A novel universalN-transfer reagent for direct and effective transformation of α-amino ketones, acetamides, and esters to the corresponding α-diazo products under mild basic conditions has been developed. This one-step synthetic approach not only allows for generation of α-substituted-α-diazo carbonyl compounds from α-amino acid derivatives but also permits preparation of α-diazo dipeptides fromN-terminal dipeptides (32 examples, up to 91%).

NOVEL TRF1 MODULATORS AND ANALOGUES THEREOF

Novel TRF1 modulators and analogues thereof. There is provided compounds of Formula I, wherein R, R1, R2 and X have meanings written in the description. Such compounds are useful as TRF1 inhibitors and, for that reason, as medicaments, in the treatment of cancer, particularly high cancer stem cell cancer like glioblastoma and lung cancer, and can be also useful for the development of additional TRF1 inhibitors and increasing knowledge about TRF1 activity.