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| Name |
CG 201 |
EINECS | N/A |
| CAS No. | 5205-82-3 | Density | g/cm3 |
| PSA | 121.34000 | LogP | 3.22720 |
| Solubility | N/A | Melting Point |
134-135°C |
| Formula | C22H28NO3•CH3O4S | Boiling Point | °Cat760mmHg |
| Molecular Weight | 465.61 | Flash Point | °C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by subcutaneous and intravenous routes. Moderately toxic by ingestion and intramuscular routes. When heated to decomposition it emits toxic fumes of NOx and SOx. See also ESTERS. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
bevonium metilsulfate;Piribenzil methyl sulfate;Bevonium |
CG 201 Chemical Properties
IUPAC Name: (1,1-Dimethylpiperidin-1-ium-2-yl)methyl 2-hydroxy-2,2-diphenylacetate; methyl sulfate
EINECS: 226-001-8
Melting point: 134–135 °C
Molecular Weight: 465.5597 g/mol
Molecular Formula : C23H31NO7S
Following is the structure:
.bmp)
Classification Code of CG 201 (CAS NO.5205-82-3 ) : Drug / Therapeutic Agent
CG 201 Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | oral | 1gm/kg (1000mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| guinea pig | LD50 | oral | 3860mg/kg (3860mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| guinea pig | LD50 | subcutaneous | 182mg/kg (182mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: EXCITEMENT BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| mouse | LD50 | intraperitoneal | 112mg/kg (112mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1423, 1969. | |
| mouse | LD50 | intravenous | 17400ug/kg (17.4mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| mouse | LD50 | oral | 1360mg/kg (1360mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| mouse | LD50 | subcutaneous | 436mg/kg (436mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| rabbit | LD50 | intramuscular | 500mg/kg (500mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| rabbit | LD50 | oral | 1gm/kg (1000mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| rat | LD50 | intraperitoneal | 222mg/kg (222mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1423, 1969. | |
| rat | LD50 | intravenous | 26mg/kg (26mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: EXCITEMENT BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| rat | LD50 | oral | 5080mg/kg (5080mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 901, 1966. |
| rat | LD50 | subcutaneous | 2400mg/kg (2400mg/kg) | Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971. |
CG 201 Safety Profile
Poison by subcutaneous and intravenous routes. Moderately toxic by ingestion and intramuscular routes. When heated to decomposition it emits toxic fumes of NOx and SOx.
CG 201 Specification
CG201 is such an improved formulation, which has been brought through preclinical evaluation studies in preparation for clinical trials in cancer patients.CG201 represents a great improvement in immunopotency over older anti-hCG vaccine formulations, yielding much higher levels of anti-hCG antibodies than possible with previous formulations. Its Synonyms are 2-(Hydroxymethyl)-1,1-dimethylpiperidinium methyl sulfate benzilate ; Acabel ; Benzilic acid ester with 2-(hydroxymethyl)-1,1-dimethylpiperidinium methyl sulfate ; Benzilsaeure-(N,N-dimethyl-2-hydroxymethyl-piperidinium)-ester-methylsulfat ; Bevonii metilsulfas ; Bevonium methyl sulfate ; Bevonium methylsulphate ; Bevonium metilsulfate ; Ester d'acide benzilique et du 1-methylsulfate de 1,1-dimethyl-(2-hydroxymethyl)piperidinium ; Ester del acido bencilico del 1,1-dimetil-2-oximetil-piperidinio-metilsulfato ; Metilsulfate de bevonium ; Metilsulfato de bevonio ; Piperidinium, 2-(hydroxymethyl)-1,1-dimethyl-, methyl sulfate, benzilate ; Piribenzil methyl sulfate ; alpha-Phenylmandelic acid N,N-dimethylpiperidinium-2-methyl ester methylsulfate .
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