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Name	CYMARIN	EINECS	208-087-9
CAS No.	508-77-0	Density	1.31 g/cm3
PSA	131.75000	LogP	2.43330
Solubility	N/A	Melting Point	148ºC
Formula	C30H44 O9	Boiling Point	722.1ºCat 760 mmHg
Molecular Weight	548.674	Flash Point	232.7 ºC
Transport Information	N/A	Appearance	N/A
Safety	Poison by intravenous, intraperitoneal, and possibly other routes. Used as a cardiotonic. When heated to decomposition it emits acrid smoke and fumes.	Risk Codes	23/25-33
Molecular Structure		Hazard Symbols	T
Synonyms	Cymarin(6CI,7CI,8CI);Alvonal MR;Cymarine;K-Strophanthin-a;NSC 7522;Strophantin K;WV 90043a;

CYMARIN Chemical Properties

Product Name: Cymarin (CAS NO.508-77-0)

Molecular Formula: C₃₀H₄₄O₉
Molecular Weight: 548.66g/mol
Mol File: 508-77-0.mol
Einecs: 208-087-9
Boiling point: 722.1 °C at 760 mmHg
Storage Temperature: 2-8°C
Flash Point: 232.7 °C
Density: 1.31 g/cm³
Surface Tension: 59.4 dyne/cm
Enthalpy of Vaporization: 120.47 kJ/mol
Vapour Pressure: 4.46E-24 mmHg at 25°C
XLogP3: 0.8
H-Bond Donor: 3
H-Bond Acceptor: 9
Product Categories: Cardioglycosides & Glycosides; Carbohydrates; Carbohydrates A to; Carbohydrates P-ZBiochemicals and Reagents; Polysaccharide

CYMARIN Uses

Cymarin (CAS NO.508-77-0) is a cardiogenic toxin that causes cardiac arrhythmia in humans. Cymarin is used in modern medicine in copiously formulated pharmaceutical preparations used to treat a variety of tumors.

CYMARIN Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LD50	intravenous	95ug/kg (0.095mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 74, Pg. 223, 1942.
cat	LD50	parenteral	110ug/kg (0.11mg/kg)		Bollettino Chimico Farmaceutico. Vol. 98, Pg. 297, 1959.
cat	LDLo	unreported	110ug/kg (0.11mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 148, Pg. 471, 1964.
mouse	LD50	intracrebral	41ug/kg (0.041mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 908, 1961.
mouse	LD50	intraperitoneal	12mg/kg (12mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 165, 1965.
mouse	LD50	intravenous	2800ug/kg (2.8mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 908, 1961.
rat	LD50	intravenous	20mg/kg (20mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 165, 1965.

CYMARIN Safety Profile

Poison by intravenous, intraperitoneal, and possibly other routes. Used as a cardiotonic. When heated to decomposition it emits acrid smoke and fumes.
Safety Information of Cymarin (CAS NO.508-77-0):
Hazard Codes: T,T+
Risk Statements: 23/25-33-26/27/28
23: Toxic by inhalation
25: Toxic if swallowed
26: Very Toxic by inhalation
27: Very Toxic in contact with skin
28: Very Toxic if swallowed
33: Danger of cumulative effects
Safety Statements: 45-36/37/39
36: Wear suitable protective clothing
37: Wear suitable gloves
39: Wear eye/face protection
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)

CYMARIN Specification

Cymarin ,its CAS NO. is 508-77-0,the synonyms is 20(22),5Beta-cardenolid-19-al-3beta,5beta,14beta-triol 3beta-mixed glycosides ; Cimarin ; Cymarine ; k Strophanthin ; k-Strophanthin-a ; k-Strophanthin-alpha ; k-Strophanthidin-d-cymaroside .

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