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 Biotechnology of succinic acid production and markets for derived industrial products
  • Biotechnology of succinic acid production and markets for derived industrial products
  • Succinic acid, derived from fermentation of agricultural carbohydrates, has a specialty chemical market in industries producing food and pharmaceutical products, surfactants and detergents, green solvents and biodegradable plastics, and ingredients to stimulate animal and plant growth. As a carbon-intermediate chemical, fermentation-derived succinate has the potential to supply over 2.765×6510 8 65kg industrial products/year including: 1,4-butanediol, tetrahydrofuran, γ-butyrolactone, adipic acid, n -methylpyrrolidone and linear aliphatic esters. Succinate yields as high as 11065g/l have been achieved from glucose by the newly discovered rumen organism Actinobacillus succinogenes . Succinate fermentation is a novel process because the greenhouse gas CO 2 is fixed into succinate during glucose fermentation. New developments in end-product recovery technology, including water-splitting electrodialysis and liquid/liquid extraction have lowered the cost of succinic acid production to U.S. $ 0.55/kg at the 7565000 tonne/year level and to $ 2.20/kg at the 5000 tonne/year level. Research directions aimed at further improving the succinate fermentation economics are discussed.8nActinobacillus succinogenes2


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