- Hell-Volhard-Zelinsky Reaction
-
Hell-Volhard-Zelinsky Reaction
C. Hell, Ber. 14, 891 (1881); J. Volhard, Ann. 242, 141 (1887); N. Zelinsky, Ber. 20, 2026 (1887).
α-Halogenation of carboxylic acids in the presence of catalytic phosphorus, presumably involving the enol form of the intermediate acyl halide:
N. O. V. Sonntag, Chem. Rev. 52, 237 (1953); H. J. Harwood, ibid. 62, 102 (1962); H. Kwart, E. V. Scalzi, ibid. 86, 5496 (1964); A. R. Sexton et al., J. Am. Chem. Soc. 91, 7098 (1969); G. L. Lange, J. A. Otulakowski, J. Org. Chem. 47, 5093 (1982); R. J. Crawford, ibid. 48, 1364 (1983); H.-J. Liu, W. Luo, Synth. Commun. 21, 2097 (1991).
Prev: Henkel Reaction
Next: Helferich Method - 【Back】【Close 】【Print】【Add to favorite 】
- Related information
- Reaction routes of Metronidazole
- Reaction Kettle_008
- Production of 4-(2-Bromo-2-propenyl)-4-methyl-γ-butyrolactone by the Reaction of Ethyl levulinate with (2-bromoallyl)diisopropoxyborane
- Double Hydroxylation Reaction: 16α-Methylcortexolone
- Diels-Alder reaction: (1S-endo)-3-(Bicyclo[2.2.1]hept-5-en-2-ylcarbonyl)-2-oxazolidinone
- 4-(2-Bromo-2-propenyl)-4-methyl-gamma-butyrolactone: from the reaction of Ethyl levulinate and (2-Bromoallyl)diisopropoxyborane
- Synthesis of trans-4,4'-Dibromostilbene by a Double Heck Reaction of (Arylazo)amines with Vinyltriethoxysilane
- Single Displacement Reactions
- Reaction Design
- Chemical Reaction Stoichiometry (CRS, Tutorial, Java Applet, and Resources)
-
Health and Chemical more >
-
Hot Products
- 70775-75-6 1-Octanamine,N,N'-(1,10-decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-, hydrochloride (1:2)
- 516-55-2 ALLOPREGNANOLONE
- 29976-53-2 N-Carbethoxy-4-piperidone
- 13772-29-7 ZIRCONIUM(IV) HYDROGENPHOSPHATE
- 56341-41-4 5-Fluoro-2-oxindole
- 204589-82-2 (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid
- 5444-75-7 BENZOIC ACID 2-ETHYLHEXYL ESTER
- 86-39-5 2-Chlorothioxanthone
- 9007-28-7 Chondroitin sulfate
- 93164-89-7 Bacopa monnieri, ext.
- 2032-35-1 Bromoacetaldehyde diethyl acetal
- 438220-65-6 Methyl 5-[(3-chloro-4-fluorophenoxy)methyl]furan-2-carboxylate