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Cas Database |
| Name |
DELAPRIL HYDROCHLORIDE |
EINECS | N/A |
| CAS No. | 83435-67-0 | Density | N/A |
| PSA | 95.94000 | LogP | 3.80250 |
| Solubility | N/A | Melting Point |
169 ℃ |
| Formula | C26H32 N2 O5 . Cl H | Boiling Point | 659.7ºC at 760 mmHg |
| Molecular Weight | 489.011 | Flash Point | 352.7ºC |
| Transport Information | N/A | Appearance | White crystalline powder |
| Safety | Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Glycine,N-(2,3-dihydro-1H-inden-2-yl)-N-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-,monohydrochloride, (S)-; Glycine,N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-N-(2,3-dihydro-1H-inden-2-yl)-,monohydrochloride (9CI); Adecut; CV 3317; Cupressin; Delapril hydrochloride;REV 6000A |
Article Data | 4 |
DELAPRIL HYDROCHLORIDE Chemical Properties
Product Name: Delapril hydrochloride (CAS NO.83435-67-0)
Molecular Formula: C26H32N2O5.HCl
Molecular Weight: 489.0036 g/mol
Mol File: 83435-67-0.mol
Appearance: White crystalline powder
Boiling point: 659.7 °C at 760 mmHg
Flash Point: 352.7 °C
Enthalpy of Vaporization: 102 kJ/mol
Vapour Pressure: 2.67E-18 mmHg at 25°C
H-Bond Donor: 3
H-Bond Acceptor: 6
DELAPRIL HYDROCHLORIDE Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 164mg/kg (164mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 15(Suppl, |
| mouse | LD50 | oral | 3120mg/kg (3120mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 15(Suppl, |
| mouse | LD50 | subcutaneous | 2340mg/kg (2340mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 15(Suppl, |
| rat | LD50 | intraperitoneal | 208mg/kg (208mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 15(Suppl, |
| rat | LD50 | oral | 8260mg/kg (8260mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 15(Suppl, |
| rat | LD50 | subcutaneous | 5900mg/kg (5900mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 15(Suppl, |
DELAPRIL HYDROCHLORIDE Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl.
DELAPRIL HYDROCHLORIDE Specification
Delapril hydrochloride ,its CAS NO. is 83435-67-0,the synonyms is Delapril hcl ; Delapril hydrochloride ; Dalapril hcl ; n-(n-((s)-1-Ethoxycarbonyl-3-phenylpropyl)-l-alanyl)-n-(indan-2-yl)gly cine hydrochloride ; Adecut ; Cupressin ; Cv 3317 ; Glycine, n-(2,3-dihydro-1h-inden-2-yl)-n-[n-[1-(ethoxycarbonyl)-3-phenylpropyl]-l-alanyl]-, monohydrochloride, (s)- .
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