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Dicofol

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Dicofol

EINECS 204-082-0
CAS No. 115-32-2 Density 1.532 g/cm3
PSA 20.23000 LogP 5.59950
Solubility <0.01 g/100 mL at 22 °C in water Melting Point 78.5 °C
Formula C14H9Cl5O Boiling Point 454.7 °C at 760 mmHg
Molecular Weight 370.49 Flash Point 228.8 °C
Transport Information UN 2761/3077 Appearance white or grey powder, or colourless crystals
Safety 36/37-60-61-45-16-7 Risk Codes 21/22-38-43-50/53-39/23/24/25-23/24/25-11
Molecular Structure Molecular Structure of 115-32-2 (Dicofol) Hazard Symbols HarmfulXn, DangerousN, ToxicT, FlammableF
Synonyms

Benzhydrol,4,4'-dichloro-a-(trichloromethyl)-(8CI);1,1-Bis(4-chlorophenyl)-2,2,2-trichloroethanol;1,1-Bis(p-chlorophenyl)-2,2,2-trichloroethanol;2,2,2-Trichloro-1,1-bis(p-chlorophenyl)ethanol;2,2,2-Trichloro-1,1-di(4-chlorophenyl)ethanol;4,4'-Dichloro-a-(trichloromethyl)benzhydrol;AFD25;Acarin;Agravertin;CPCA;Decofol;Dichlorokelthane;Dicofol;ENT 23,648;Ethanol, 2,2,2-trichloro-1,1-bis(4-chlorophenyl)-;FW 293;Kelthane;Kelthane A;Milbol;Mitigan;p,p'-Kelthane;

Article Data 13

Dicofol Chemical Properties

   The molecular formula of 1,1-BIS(p-CHLOROPHENYL)-2,2,2-TRICHLORO-ETHANOL(115-32-2) is C14H9Cl5O and its formula weight is 370.48g/mol.Its EINECS is 204-082-0 and liansport information is UN 2761/3.The appearance of 1,1-BIS(p-CHLOROPHENYL)-2,2,2-TRICHLORO-ETHANOL (115-32-2) is white or grey powder, or colourless crystals.The density of 1,1-BIS(p-CHLOROPHENYL)-2,2,2-TRICHLORO-ETHANOL (115-32-2) is 1.45 g/cm3 and it has a melting point of 78.5°C.The boiling point is 454.7 °C at 760 mmHg.The refractive index is about 1.626 and molar refractivity is 85.61 cm3.Molar volume is 241.8 cm3 and polarizability is 33.93 10-24cm3.Surface tension is 51.8 dyne/cm and enthalpy of vaporization is 75.28 kJ/mol.Its flash point is 228.8 °C and the vapor pressure is 4.64E-09 mmHg at 25°C.1,1-BIS(p-CHLOROPHENYL)-2,2,2-TRICHLORO-ETHANOL (115-32-2) has the property of being dissolved in acetone, ethyl acetate, xylene and other organic solvents,slightly dissolved in water.The solubility of 1,1-BIS(p-CHLOROPHENYL)-2,2,2-TRICHLORO-ETHANOL (115-32-2) is less than 0.01 g/100 mL in water at 22°C.It is stable and combustible.It is incompatible with strong oxidizing agents and hydrolyzes in basic solution.It corrodes some metals. 
   The chemical synonyms of 1,1-BIS(p-CHLOROPHENYL)-2,2,2-TRICHLORO-ETHANOL (115-32-2) are 1,1,1-Trichlor-2,2-bis(4-chlorphenyl)-aethanol;1,1-Bis(4-chlorophenyl)-2,2,2-trichloroethanol;2,2,2-Trichloor-1,1-bis(4-chloor fenyl)-ethanol;2,2,2-trichloor-1,1-bis(4-chloorfenyl)-ethanol;2,2,2-Trichlor-1,1-bis(4-chlor-phenyl)-aethanol;2,2,2-trichloro-1,1-bis(4-chlorophenyl)-ethanol(french);2,2,2-Trichloro-1,1-bis(4-cloro-fenil)-etanolo and 2,2,2-trichloro-1,1-bis(p-chlorophenyl)-ethano.Its product categories is INSECTICIDE;2000/60/EC;Alphabetic;Analytical Standards;European Community: ISO and DIN;KMethod Specific;AcaricidesPesticides&Metabolites;Alpha sort;D;DAlphabetic;DIA - DICMethod Specific;Endocrine Disruptors (Draft);EPA;Pesticides and Metabolites. The molecular structure of 1,1-BIS(p-CHLOROPHENYL)-2,2,2-TRICHLORO-ETHANOL (115-32-2) is .

Dicofol Uses

It is used in cancer bioassay and  as miticid.

Dicofol Toxicity Data With Reference

1.   

sce-hmn:lym 1 µmol/L

   ARTODN    Archives of Toxicology. 52 (1983),221.
2.   

orl-rat LD50:575 mg/kg

   WRPCA2    World Review of Pest Control. 9 (1970),119.
3.   

skn-rat LD50:100 mg/kg

   WRPCA2    World Review of Pest Control. 9 (1970),119.
4.   

ipr-rat LD50:1150 mg/kg

   TXAPA9    Toxicology and Applied Pharmacology. 15 (1969),30.
5.   

orl-mus LD50:420 mg/kg

   GTPZAB    Gigiena Truda i Professionalnye Zabolevaniia. Labor Hygiene and Occupational Diseases. 19 (9)(1975),55.
6.   

orl-rbt LD50:1810 mg/kg

   TXAPA9    Toxicology and Applied Pharmacology. 1 (1959),119.
7.   

skn-rbt LD50:1870 mg/kg

   GUCHAZ    Guide to the Chemicals Used in Crop Protection 6 (1973),195.
8.   

orl-gpg LD50:1810 mg/kg

   85DPAN    Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel Werner Perkow, Berlin, Germany.: Verlag Paul Parey,1971/76
9.   

orl-ckn LD50:4365 mg/kg

   VETNAL    Veterinariya. 60 (10)(1984),64.

Dicofol Consensus Reports

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 30 (1983),p. 87.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Bioassay (feed); Clear Evidence: mouse NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-90 ,1978. ; No Evidence: rat NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-90 ,1978. . Community Right-To-Know List.

Dicofol Safety Profile

Poison by ingestion and skin contact. Moderately toxic by intraperitoneal route. Human mutation data reported. Questionable carcinogen with experimental carcinogenic data. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl.
Hazard symbols is Xn;N;T;F.
Risk statements is 21/22-38-43-50/53-39/23/24/25-23/24/25-11.
20/21:  Harmful by inhalation and in contact with skin.
23/24/25:  Toxic by inhalation, in contact with skin and if swallowed.
39/23/24/25:  Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed.
50/53:  Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
38:  Irritating to the skin.
43:  May cause sensitization by skin contact.
11:  Highly Flammable.              
Safety statements is 36/37-60-61-45-16-7.
36/37:  Wear suitable protective clothing and gloves.
60:  This material and/or its container must be disposed of as hazardous waste. 
61:  Avoid release to the environment. Refer to special instructions safety data sheet.
16:  Keep away from sources of ignition - No smoking.
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible).
7:  Keep container tightly closed.

Dicofol Specification

Its extinguishing agent is sand, dry powder and foam.
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